Histoplasmosis

Sykes, Jane E.; Taboada, Joseph

doi:10.1016/b978-1-4377-0795-3.00061-2

Cited by 16 publications

(15 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Nelson & Couto (2015) afirmam que todos os gatos possuem o prognóstico de reservado a grave. Em contrapartida, Sykes & Taboada (2014) afirmam que animais que não estejam severamente debilitados apresentam prognóstico favorável após um tratamento prolongado com itraconazol. Desta forma, o presente relato discorda dos autores, visto que houve resolução clínica rápida da afecção após início do tratamento.…”

Section: Pubvetunclassified

Histoplasmosis nasal en un gato: reporte de un caso

Accioly¹,

Ferreira²,

Morais³

et al. 2020

Pubvet

View full text Add to dashboard Cite

A histoplasmose é uma doença fúngica sistêmica, causada pelo fungo Histoplasma capsulatum, este caracteriza-se por ser dimórfico e saprófita. Esta patologia pode ter caráter clínico agudo ou crônico e resultar em infecção subclínica, pulmonar ou disseminada, caracteriza-se por ser a segunda micose de maior ocorrência nos gatos e nesses apresenta baixa morbidade e altas taxas de mortalidade. O diagnóstico pode ser obtido pela cultura fúngica e o tratamento é realizado principalmente a base de itraconazol. Objetivando relatar um caso clínico de histoplasmose felina realizou-se o presente trabalho. Foi atendido um gato sem raça definida, fêmea, de quatro anos de idade, com queixa principal de aumento de volume nasal. Foram solicitados inicialmente exames hematológicos, bioquimicos, citológico da nodulação no plano nasal, teste imunocromatográfico para imunodeficiencia viral felina e leucemia viral felina, e sete dias após, foi solicitada a cultura fúngica. Nos exames hematológicos observou-se trombocitopenia, agregados plaquetários, leucocitose por neutrofilia e hipoalbuminemia. O exame imunocromatográfico para ambas as retroviroses foi negativo. No exame citopatológico foram encontradas estruturas leveduriformes sugestivas de Criptococcus sp.,todavia, na cultura fúngica essas estruturas foram compatíveis com Histoplasma capsulatum. Baseado no resultado do exame citológico, foi prescrito para a paciente itraconazol 10 mg/kg duas vezes ao dia durante 60 dias, este deveria ser iniciado após a realização da cultura fúngica. O animal apresentou melhora significativa a partir de 7 dias do uso do medicamento, com regressão total da nodulação após 26 dias de tratamento. Após os 2 meses de tratamento, houve suspensão da medicação por 19 dias por decisão da tutora e retorno da administração por mais 30 dias no intuito de evitar a remissão da patologia. Com isso pode-se concluir que a histoplasmose nasal é uma afecção fúngica presente na rotina clínica de felinos, exigindo assim do médico veterinário atenção para a sintomatologia e métodos de diagnósticos complementares, bem como, a realização do tratamento e prognóstico de forma correta.

show abstract

Section: Pubvetunclassified

Histoplasmosis nasal en un gato: reporte de un caso

Accioly¹,

Ferreira²,

Morais³

et al. 2020

Pubvet

View full text Add to dashboard Cite

show abstract

“…Soils act as reservoirs for Histoplasma , especially where temperatures are 22°C–29°C and annual rainfall is 35–50 inches ( 2 ). According to a 1969 map by Edwards et al of histoplasmin skin test reactivity among single-county-resident Navy recruits in the United States, H. capsulatum has been most prevalent in the Mississippi and Ohio River basins ( 3 ).…”

mentioning

confidence: 99%

MappingHistoplasma capsulatumExposure, United States

Maiga¹,

Deppen²,

Scaffidi³

et al. 2018

Emerg. Infect. Dis.

View full text Add to dashboard Cite

Maps of Histoplasma capsulatum infection prevalence were created 50 years ago; since then, the environment, climate, and anthropogenic land use have changed drastically. Recent outbreaks of acute disease in Montana and Nebraska, USA, suggest shifts in geographic distribution, necessitating updated prevalence maps. To create a weighted overlay geographic suitability model for Histoplasma, we used a geographic information system to combine satellite imagery integrating land cover use (70%), distance to water (20%), and soil pH (10%). We used logistic regression modeling to compare our map with state-level histoplasmosis incidence data from a 5% sample from the Centers for Medicare and Medicaid Services. When compared with the state-based Centers data, the predictive accuracy of the suitability score–predicted states with high and mid-to-high histoplasmosis incidence was moderate. Preferred soil environments for Histoplasma have migrated into the upper Missouri River basin. Suitability score mapping may be applicable to other geographically specific infectious vectors.

show abstract

“…Clinical signs of the disseminated gastrointestinal form are usually nonspecific and similar to other chronic gastrointestinal pathologies such as chronic diarrhea, weight loss, hyporexia, or anorexia and lethargy. Rectal and colonic scraping and cytology is the least invasive and most easily performed test for diagnosing gastrointestinal histoplasmosis; however, sometimes repeated attempts are needed because the microorganism is not uniformly distributed 8,9 . Other diagnostics such as lymph node cytology, histopathology, fungal culture, antigen testing, or serology can aid in diagnosing the disease 3,9 .…”

Section: Introductionmentioning

confidence: 99%

“…Rectal and colonic scraping and cytology is the least invasive and most easily performed test for diagnosing gastrointestinal histoplasmosis; however, sometimes repeated attempts are needed because the microorganism is not uniformly distributed 8,9 . Other diagnostics such as lymph node cytology, histopathology, fungal culture, antigen testing, or serology can aid in diagnosing the disease 3,9 . In cases of suspected or confirmed gastrointestinal histoplasmosis, abdominal ultrasound might be pursued to fully evaluate the gastrointestinal tract.…”

Section: Introductionmentioning

confidence: 99%

Ultrasonographic findings of gastrointestinal histoplasmosis in dogs

Berle

KuKanich

Biller

2020

Vet Radiology Ultrasound

View full text Add to dashboard Cite

Histoplasmosis, a mycotic infection caused by Histoplasma spp, can infect the gastrointestinal tract of dogs. Clinical signs of gastrointestinal histoplasmosis can include diarrhea, profound weight loss, anorexia, and vomiting. Rectal scrape for cytology can provide a quick diagnosis, but if negative abdominal ultrasound is often pursued. Ultrasonographic abnormalities in dogs with gastrointestinal histoplasmosis have rarely been reported. This retrospective, single-center case series aimed to describe the ultrasonographic features of gastrointestinal histoplasmosis in dogs. Nineteen cases with a diagnosis of gastrointestinal histoplasmosis confirmed with gastrointestinal cytology or histopathology (N = 15) or gastrointestinal lymph node cytology (N = 4) that had undergone an abdominal ultrasound examination from 2005 to 2020 were included. Ultrasound images were reviewed by an American College of Veterinary Radiology (ACVR)-certified veterinary radiologist and diagnostic imaging resident. Eighteen cases had sonographic abnormalities within the gastrointestinal tract. The colon was the most affected organ. Colonic thickening and abnormal wall layering were the most frequent findings (N = 16 dogs); thickening ranged from 0.36 to 1.2 cm. Diffuse, multifocal, and focal thickening patterns were seen. Sixteen patients had abnormal wall layering of the colon (complete loss of layering or altered with partial loss of layering). Other frequent findings included lymphadenopathy, small intestinal thickening with abnormal wall layering and peritoneal effusion. Based on the authors' review of the literature, this is the first description of ultrasonographic findings of gastrointestinal histoplasmosis in a group of dogs. Although abnormal gastrointestinal wall layering seen sonographically is most frequently associated with neoplasia, this is not pathognomonic. Gastrointestinal histoplasmosis should be considered as a differential diagnosis due to the similarities and overlap of ultrasonographic features.

show abstract

Histoplasmosis

Cited by 16 publications

References 43 publications

Histoplasmosis nasal en un gato: reporte de un caso

Histoplasmosis nasal en un gato: reporte de un caso

MappingHistoplasma capsulatumExposure, United States

Ultrasonographic findings of gastrointestinal histoplasmosis in dogs

Contact Info

Product

Resources

About