2021
DOI: 10.34172/ps.2021.35
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Historical Course of Neuropsychiatric Effects of Lemon Balm (Melissa Officinalis L.) as a Medicinal Herb

Abstract: Affective disorders have become prevalent and costly worldwide chronic conditions. Lemon Balm (Melissa Officinalis L.) is a medicinal plant with beneficial effects on neuropsychiatric disorders. Its potential to specifically treat conditions such as depression and anxiety has been investigated for over 20 centuries. Given the lack of a historical overview of lemon balm in mood disorders, the present review aimed to introduce the historical course of the neuro-psychiatric applications of lemon balm across the c… Show more

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“…The anxiolytic activity of citrus aurantium L. was mediated by the serotonergic system (5-HT1A receptor) (7,70). Interestingly, citrus aurantium L. significantly ameliorated anxiety and did not interfere with physiological levels of melatonin and corticosterone (71). Thus, it could be reasonably inferred that citrus aurantium L. EO has the greatest benefits in treating anxiety.…”
Section: Possible Explanation For Study Findingsmentioning
confidence: 97%
“…The anxiolytic activity of citrus aurantium L. was mediated by the serotonergic system (5-HT1A receptor) (7,70). Interestingly, citrus aurantium L. significantly ameliorated anxiety and did not interfere with physiological levels of melatonin and corticosterone (71). Thus, it could be reasonably inferred that citrus aurantium L. EO has the greatest benefits in treating anxiety.…”
Section: Possible Explanation For Study Findingsmentioning
confidence: 97%