Historical Evolution of the Use of Minerals in Human Health

Gomes, Celso; Rautureau, Michel

doi:10.1007/978-3-030-65706-2_3

Cited by 5 publications

(12 citation statements)

References 74 publications

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“…Nutrigenomics is the study of how nutrients change gene expression by having a direct effect on the genome or indirectly by regulating biological mechanisms [ 10 , 12 , 17 , 18 ]. This field of study began after the completion of the Human Genome Project in 2003 [ 10 , 12 , 16 ].…”

Section: Nutrigenomics In Cancer Therapymentioning

confidence: 99%

“…Understanding the nutrigenomics of nutrients can allow for personalized nutrition therapies to be used in the prognosis, treatment, and prevention of cancer on the basis of which nutrients have a protective effect on the body [ 10 ]. Nutrients affect gene regulation, which impacts epigenomic, transcriptomic, proteomic, or metabolomic pathways [ 17 , 18 ]. Each nutrient affects these pathways in different ways, resulting in different effects [ 18 , 19 ].…”

Section: Nutrigenomics In Cancer Therapymentioning

confidence: 99%

“…Nutrients affect gene regulation, which impacts epigenomic, transcriptomic, proteomic, or metabolomic pathways [ 17 , 18 ]. Each nutrient affects these pathways in different ways, resulting in different effects [ 18 , 19 ]. Further investigation of nutrigenomic aspects of cancer can aid in the prevention and treatment of cancer.…”

Section: Nutrigenomics In Cancer Therapymentioning

confidence: 99%

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Role of Antioxidant Vitamins and Other Micronutrients on Regulations of Specific Genes and Signaling Pathways in the Prevention and Treatment of Cancer

Fagbohun

Gillies

Murphy

et al. 2023

IJMS

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Cancer is an escalating global issue, with 19.3 million new cases and 9.9 million deaths in 2020. Therefore, effective approaches to prevent cancer are urgently required. Diet plays a significant role in determining cancer risk. Nutrients and food bioactives influence specific signaling pathways in the body. Recently, there have been significant advances in cancer prevention research through nutrigenomics or with the effects of dietary components on the genome. Google Scholar, PubMed, and Scopus databases were used to search for peer-reviewed articles between 2017 and 2023. Criteria used were vitamins, minerals, tumors, cancer, genes, inflammation, signaling pathways, and nutrigenomics. Among the total of 1857 articles available, the highest relevant 90 articles that specifically discussed signaling pathways and genes on cancer cell lines and human cancer patients were selected and reviewed. Food sources are rich in antioxidant micronutrients, which are effective in activating or regulating signaling pathways involved in pathogenesis and cancer therapy by activating enzymes such as mitogen-activated protein kinase (MAPK), protein kinase C (PKC), and phosphatidylinositol 3-kinase (PI3K). The micronutrients are involved in the regulation of β-catenin (WNT/β-catenin) including mutations in Kras and epidermal growth factor receptor (EGFR) alongside inhibition of the NF-kB pathway. The most common mechanism of cancer prevention by these micronutrients is their antioxidative, anti-inflammation, and anti-apoptosis effects. This review discusses how nutrigenomics is essential and beneficial for developing cancer prevention and treatment approaches.

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Section: Nutrigenomics In Cancer Therapymentioning

confidence: 99%

Section: Nutrigenomics In Cancer Therapymentioning

confidence: 99%

Section: Nutrigenomics In Cancer Therapymentioning

confidence: 99%

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Role of Antioxidant Vitamins and Other Micronutrients on Regulations of Specific Genes and Signaling Pathways in the Prevention and Treatment of Cancer

Fagbohun

Gillies

Murphy

et al. 2023

IJMS

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“…The natural, inorganic, solid, and crystalline compounds that undergoes manmade physical and chemical modifications, and is able to change, in a controllable mode, its natural physical and chemical properties assumed to be important for certain industrial applications, situation exemplified by the processes: delamination, intercalation, pillaring, and acid or alkaline activation being performed in certain clay minerals. 3. The bio-essential chemical elements of natural origin that, in the ionic form, are constituents of the solid food of either vegetable or animal nature being created in soil, which being named macronutrients or mineral salts and micronutrients or oligominerals are the main suppliers and carriers of minerals for human nutrition and wellness.…”

Section: Prefacementioning

confidence: 99%

“…Help the maintenance of normal heart rate, muscle contraction and conduction of the nervous system, and acid-base balance. 3. Regulate cellular metabolism by being part of enzymes and hormones that control cellular activity.…”

Section: Prefacementioning

confidence: 99%

Minerals latu sensu and Human Health

2021

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The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2021 This work is subject to copyright. All rights are solely and exclusively licensed by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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