History of Acne and Rosacea

Plewig, Gerd; Kligman, Albert M.

doi:10.1007/978-3-642-59715-2_1

Cited by 69 publications

(109 citation statements)

References 23 publications

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“…A prior history of facial redness is common, but to a lesser extent than in patients affected by the erythematotelangiectatic subtype. Most patients are middle-aged women (9), and the condition is not so frequently triggered by external stimuli (10). In phyma-type rosacea a marked thickening of the skin develops in association with superficial nodularity, which may be found in the nose (rhinophyma), ears (otophyma), chin (gnatophyma), forehead (metophyma) or eyelids (blepharophyma) (11).…”

Section: Introductionmentioning

confidence: 99%

Effect of Helicobacter pylori eradication therapy in rosacea patients

Miquel

Romero

Sequeiros

et al. 2006

Rev. esp. enferm. dig.

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Objective: the causal relation between rosacea and Helicobacter pylori infection is discussed. We evaluated the clinical evolution of rosacea after infection eradication.Patients and methods: we have prospectively studied 44 patients diagnosed with rosacea. Helicobacter pylori infection was determined, and infected patients were treated with eradication therapy. The evolution of dermatological symptoms in a subgroup of 29 infected patients in whom eradication had been achieved was followed during 16.8 (± 17.8) months. Median age was 50.6 (± 14.1) years for 22 women (75.9%) and 7 men (24.1%). Clinical response according to gender and clinical subtype of rosacea was evaluated.Results: complete improvement was observed in 10 patients (34.5%; 95% CI: 18.6-54.3%), relevant improvement in 9 (31.1%; 95% CI: 16-51%), poor improvement in 5 (17.2%; 95% CI: 6.5-36.4%), and absence of improvement in 5 cases (17.2%; 95% CI: 6.5-36.4%). No significant differences in dermatological evolution according to sex were observed. Regarding subtype of rosacea there was a relevant improvement in 83.3% (95% CI: 64.1-93.8%) of cases with papulopustular type as opposed to 36.5% (95% CI: 20-56.1%) of cases with erythematous predominance, p = 0.02.Conclusions: based on these results, the relation between Helicobacter pylori and rosacea is supported, and infection should be investigated in these patients because an appreciable percentage of patients diagnosed with rosacea and Helicobacter pylori infection can benefit from eradication therapy, mainly in the papulopustular subtype.

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Section: Introductionmentioning

confidence: 99%

Effect of Helicobacter pylori eradication therapy in rosacea patients

Miquel

Romero

Sequeiros

et al. 2006

Rev. esp. enferm. dig.

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“…According to Plewig and Kligman [28], the word ‘comedo' appeared in writings of Velschius (1764) [138]. In Plenck's Doctrina [10], closed comedones are recognizable under the name ‘grutum sine milium'.…”

Section: Comedogenesis: From the Horny Plug To The Biofilm Theorymentioning

confidence: 99%

“…Only very few of them dealt with the history of the disease focusing on semantic considerations (see above) or quoting the main authors and their works [26]. Parish and Witkowski [27] and more recently Plewig and Kligman [28] gave illustrated accounts of the history of acne, summarizing milestones in chronological order. To the best of our knowledge, the genesis and development of the 4 factors that constitute the pathogenic framework of acne have not been studied from a historical point of view.…”

Section: Introductionmentioning

confidence: 99%

Acne Pathogenesis: History of Concepts

Tilles¹

2014

Dermatology

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From the first reliable descriptions of acne in the early 19th century, dermatologists recognized it as a disease of the pilosebaceous follicle. Until the middle of the 20th century, they hypothesized that seborrhoea, follicular keratosis and microorganisms could be individually responsible for the acne lesions. Inflammation was only regarded as the final and inescapable step of the acne process. Although the importance of these factors has been reevaluated, recent works still regarded them as mandatory. In the 1970s, the onset of isotretinoin dramatically improved acne management. It also provided great opportunities for a better understanding of the pathogenic factors of acne. This study analyzes their genesis and development from the seminal contributions until recent advances.

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“…Эти варианты отражают наиболее рас-пространенные сочетания признаков и симптомов розацеа. Данные варианты совпадают с первой ста-дийной классификацией, предложенной Плевигом и Клигманом [23]. Эритематозно-телеангиэктатиче-ский вариант является аналогом I стадии болезни по Плевигу-Клигману, папулопустулезный вариант аналогичен II стадии по Плевигу-Клигману и фи-матозный вариант -III стадии по Плевигу-Клиг-ману.…”

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