History of supercritical fluid chromatography: Instrumental development

Saito, Muneo

doi:10.1016/j.jbiosc.2012.12.008

Cited by 163 publications

(85 citation statements)

References 68 publications

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“…Different from the commonly used chiral separation technique, HPLC and UPLC, SFC uses supercritical carbon dioxide (SCCO 2 ) as the mobile phase, its density and solvent power are similar to liquid and the viscosity and diffusivity are close to gas [11]. Owing to the high diffusivity and low viscosity of SCCO 2 , SFC is an environmentally friendly, fast and high-throughput separation approach.…”

Section: Introductionmentioning

confidence: 99%

Supercritical Fluid Chromatography and Its Application in Lipid Isomer Separation

2017

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Supercritical fluid chromatography (SFC), which uses supercritical fluid with higher diffusivity and lower viscosity than liquid as its mobile phase, can provide fast, green, high-throughput and good performance methods for the analysis of complicated samples. It is an advantageous alternative for the separation of polar and nonpolar compounds, and even chiral isomers. As an important constituent of living organisms, lipids and the related lipidomics researches have attracted dramatic attention during the past years. The separation and identification of lipids and lipid isomers are of great significance and remain challenging. In this mini-review, the principle of SFC and its applications in lipid isomer separation are summarized.

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Section: Introductionmentioning

confidence: 99%

Supercritical Fluid Chromatography and Its Application in Lipid Isomer Separation

2017

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“…This allows valuable comparison of different compounds under various conditions, but deviations can be substantial in close proximity to the critical point [13]. and pressure and there exists density inhomogeneity in the critical region.…”

Section: Introductionmentioning

confidence: 99%

Nanotechnology and supercritical fluids

Hamidreza¹,

Reza²,

Mahdi³

et al. 2016

J. Fundam and Appl Sci.

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Supercritical fluid (SCF) technology has become an important tool of materials processing in the last two decades. Supercritical CO 2 and H 2 O are extensively being used in the preparation of a great variety of nanomaterials. The interest in the preparation and application of nanometer size materials is increasing since they can exhibit properties of great industrial interest. Several techniques have been proposed to produce nanomaterials using supercritical fluids. These processes, taking advantage of the specific properties of supercritical fluids, are generally flexible, more simplified and with a reduced enviromental impact. The result is that nanomaterials with potentially better performances have been obtained. We propose a critical review of the supercritical based techniques applied to the production of nanoparticles materials.

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“…high permeability and low viscosity) and their solubility resemble those of liquid solvents. Due to these properties, supercritical fluids are used in a wide range of purification, extraction and separation processes [2]. Processes involving supercritical fluids are sustainable, eco-friendly, cost-effective and provide numerous possibilities to produce new products.…”

Section: Introductionmentioning

confidence: 99%