History repeats itself in Japan: Failure to learn from rubella epidemic leads to failure to provide the HPV vaccine

Tanaka, Yusuke; Ueda, Yutaka; Yoshino, Kiyoshi; Kimura, Tadashi

doi:10.1080/21645515.2017.1327929

Cited by 14 publications

(10 citation statements)

References 7 publications

(11 reference statements)

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“…To control rubella, vaccination is required (Zanetta et al, 2003;Wesolowski et al, 2016). As vaccination could elevate the age at infection (Amaku et al, 2003;Berger et al, 2011;Mossong et al, 2008;Tanaka et al, 2017;Saito et al, 2018), controversial routine immunization with low vaccination coverage is known to be accompanied by an increase in CRS (Best et al, 2005;Chua et al, 2015;Panagiotopoulos et al, 1999). To eliminate rubella by means of mass vaccination, high coverage of the entire population is required to attain sufficient herd immunity (Anderson and Grenfell, 1986;Massad et al, 1995;Panagiotopoulos et al, 1999;Cutts et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Predicting congenital rubella syndrome in Japan, 2018–2019

Lee

Kayano

Nishiura

2019

International Journal of Infectious Diseases

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A B S T R A C TObjectives: A rubella epidemic has been ongoing in Japan since August 2018. In the present study, we aimed to predict the likely size of a congenital rubella syndrome (CRS) epidemic during 2018-19. Methods: The expected number of CRS cases was estimated using an integral equation based on agespecific incidence of rubella among adult women, the time delay from gestational age of infection to diagnosis of CRS, and distribution of the mothers' age at delivery. We used epidemic data during 2012-14 to parameterize the model and applied this in the prediction for 2018-19. Results: In analyzing the 2012-14 epidemic data, the mean delay from the mother's infection to diagnosis was estimated at 24.2 weeks (95% confidence interval (CI): 20.7, 28.1). Applying the parameterized model, together with the more than 480 rubella cases in women in 2018 as well as delayed mother's age at delivery in 2017, we determined that the expected number of CRS cases would be 9.7 (95% CI: 6.5, 12.5) cases. As the epidemic is ongoing, the cumulative number of CRS cases could potentially reach 96.8 (95% CI: 65.3, 125.5) cases, if rubella cases in adult women rose to 10 times the number by week 49 in 2018. Conclusions: CRS is expected to occur an average of 24 weeks following the mother's infection with rubella virus. Accounting for an increase to 650 cases in women by week 5 in 2019, the expected number of CRS cases during 2018-19 has already exceeded 13 cases, as of week 5 in 2019.

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Section: Introductionmentioning

confidence: 99%

Predicting congenital rubella syndrome in Japan, 2018–2019

Lee

Kayano

Nishiura

2019

International Journal of Infectious Diseases

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“…However, because of reports of aseptic meningitis following the MMR vaccine, the Japanese government withdrew its recommendation for the MMR vaccine in 1993. [15] Human papillomavirus (HPV) vaccination for girls ages 12–16 was first licensed in Japan in October 2009. Acceptance initially reached over 70%, but it fell to less than 1% after extensive media reports of possible adverse events.…”

Section: Textmentioning

confidence: 99%

Corowa-kun: Impact of a COVID-19 vaccine information chatbot on vaccine hesitancy, Japan 2021

Kobayashi

Nishina

Tomoi

et al. 2021

Preprint

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Background: Few studies have assessed how mobile messenger apps affect COVID-19 vaccine hesitancy. We created a COVID-19 vaccine information chatbot in a popular messenger app in Japan to answer commonly asked questions. Methods: LINE is the most popular messenger app in Japan. Corowa-kun, a free chatbot, was created in LINE on February 6, 2021. Corowa-kun provides instant, automated answers to frequently asked COVID-19 vaccine questions. In addition, a cross-sectional survey assessing COVID-19 vaccine hesitancy was conducted via Corowa-kun during April 5 to 12, 2021. Results: A total of 59,676 persons used Corowa-kun during February to April 2021. Of them, 10,192 users (17%) participated in the survey. Median age was 55 years (range 16 to 97), and most were female (74%). Intention to receive a COVID-19 vaccine increased from 59% to 80% after using Corowa-kun (p < 0.01). Overall, 20% remained hesitant: 16% (1,675) were unsure, and 4% (364) did not intend to be vaccinated. Factors associated with vaccine hesitancy were: age 16 to 34 (odds ratio [OR] = 3.7, 95% confidential interval [CI]: 3.0-4.6, compared to age ≥ 65), female sex (OR = 2.4, Cl: 2.1-2.8), and history of another vaccine side-effect (OR = 2.5, Cl: 2.2-2.9). Being a physician (OR = 0.2, Cl: 0.1-0.4) and having received a flu vaccine the prior season (OR = 0.4, Cl: 0.3-0.4) were protective. Conclusions: Corowa-kun reduced vaccine hesitancy by providing COVID-19 vaccine information in a messenger app. Mobile messenger apps could be leveraged to increase COVID-19 vaccine acceptance.

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“…rubella-containing vaccine termed the measles-rubella (MR) vaccine, was started in 2006, but was soon changed to two doses; one in the first year of life and the other in infancy, one year before entering elementary school (6)(7)(8). With the full reporting of measles and rubella cases that began in 2008 ( 9), rubella immunization retargeted male and female infants, focusing on the age group receiving inadequate immunization (8,(10)(11). Further, following the nationwide measles epidemic that began in 2007 mainly among people in their teens and twenties, a second round of vaccination with the MR vaccine was offered to those who were in their first year of junior high school and those equivalent to the age of high school seniors over a 5-year period from 2008 to 2012 to immunize these individuals against rubella, a disease that should be treated together with measles (12).…”

Section: Accepted Manuscriptmentioning

confidence: 99%