Histosurgical mapping of endoscopic endonasal surgery of sinonasal tumours to improve radiotherapy guidance

Leleu, T.; Bastit, Vianney; Doré, M.; Kammerer, Emmanuel; Florescu, C.; Alfonsi, M.; Troussier, I.; Bensadoun, René-Jean; Biau, J.; Blais, E.; Deberne, M.; Wiazzane, N.; Dupin, Charles; Faivre, J.-C.; Giraud, P.; Gräff, P.; Guihard, S.; Huguet, F.; Janoray, G.; Liem, X.; Pointreau, Y.; Racadot, S.; Schick, Ulrike; Servagi-Vernat, S.; Sun, Xu; Thureau, S.; Villa, Julie; Vulquin, N.; Wong, Shelley; Patron, Vincent; Thariat, Juliette

doi:10.1016/j.canrad.2021.06.014

Cited by 4 publications

(2 citation statements)

References 28 publications

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“…It is important to understand that de-escalation using dose-painting IMRT does not aim at omitting irradiation on the sinonasal cavities but rather to tailor the dose to the level of risk to the quality of margins assessed on each small endoscopically resected tissue fragment. However, due to the lack of specific sinonasal atlases identifying endoscopic resection fragments, the anatomic uncertainties and the level of confidence of using histosurgical mapping by radiation oncologists may limit the use of dose-painting IMRT in daily practice [79]. The multistep multidisciplinary approach requires training and should become more systematic [79].…”

Section: Radiotherapy Planning After Endoscopic Endonasal Surgerymentioning

confidence: 99%

“…However, due to the lack of specific sinonasal atlases identifying endoscopic resection fragments, the anatomic uncertainties and the level of confidence of using histosurgical mapping by radiation oncologists may limit the use of dose-painting IMRT in daily practice [79]. The multistep multidisciplinary approach requires training and should become more systematic [79]. Two trials are currently investigating de-escalation in high-dose volumes.…”

Section: Radiotherapy Planning After Endoscopic Endonasal Surgerymentioning

confidence: 99%

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Precision Postoperative Radiotherapy in Sinonasal Carcinomas after Endonasal Endoscopic Surgery

Thariat

Carsuzaa

Marcy³

et al. 2021

Cancers

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Radiotherapy plays an important role in the treatment of sinonasal cancer, mainly in the adjuvant setting after surgical resection. Many technological approaches have been described, including intensity-modulated radiotherapy, concomitant chemoradiotherapy, charged particle therapy or combined approaches. The choice is based on general criteria related to the oncological results and morbidity of each technique and their availability, as well as specific criteria related to the tumor (tumor extensions, pathology and quality of margins). The aims of this review are: (i) to provide an overview of the radiotherapy techniques available for the management of sinonasal malignant tumors and (ii) to describe the constraints and opportunities of radiotherapy owing to the recent developments of endonasal endoscopic surgery. The indication and morbidity of the different techniques will be discussed based on a critical literature review.

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Section: Radiotherapy Planning After Endoscopic Endonasal Surgerymentioning

confidence: 99%

Section: Radiotherapy Planning After Endoscopic Endonasal Surgerymentioning

confidence: 99%