Histotopochemische Untersuchung über die Reaktion klinisch unbefallener Psoriatikerhaut auf Hornschichtabrisse

Abstract

The course of the epidermal regeneration after stripping of the corneal layer was comparatively investigated by means of the distribution and activity of various enzymes in clinically normal psoriatic skin and normal skin. The following results were obtained: (1) At first clinically healthy psoriatic skin and normal skin behave principally uniform. (2)The observed augmentation of the activity of various enzymes in psoriatic skin free from specific lesions is so much increased that it essentially corresponds to the condition of the psoriatic lesion although to a different intensity. (3) Differences in the reproduction of the corneal layer were observed. (4) The possible consequences of these findings for the course of the psoriatic reaction are discussed.