“…It was shown that virus induced oncolysis results in apoptosis, necrosis, necroptosis, pyroptosis, or autophagy that releases signal molecules with a pathogen-associated molecular pattern (PAMP). Infected cells also release damage-associated molecules (DAMP), including HMGB1, heat shock proteins (HSP), intracellular matrix proteins, DNA, ATP, uric acid, or heparin sulphate [ 51 , 52 ]. These molecules stimulate the innate immune response and attract antigen-presenting cells (APCs).…”