HIV-1 Tat-mediated protein transduction of Cu,Zn-superoxide dismutase into pancreatic β cells in vitro and in vivo

Inhibition of LPS-induced nitric oxide production by transduced Tat-arginine deiminase fusion protein in Raw 264.7 cells

“…Similar observations indicate that artifacts of protein transduction are not induced by paraformaldehyde fixation (36). We have also observed that the transduction of various PTD-fusion proteins into cells was not affected by paraformaldehyde fixation (29,31).…”

“…By using this protein transduction technology, we have reported that various fusion proteins were efficiently transduced into mammalian cells and animal tissues. These transduced fusion proteins markedly protected cells and http://bmbreports.org BMB reports tissues against reactive oxygen species (28)(29)(30)(31). Recently, we demonstrated that PTD fusion proteins or PTD signal peptides can be efficiently transduced into cells and maintain their enzymatic activities (32)(33)(34).…”

HIV-1 Tat-mediated protein transduction of human brain creatine kinase into PC12 cells

“…Similar observations indicate that artifacts of protein transduction are not induced by paraformaldehyde fixation (29). We have also observed that the transduction of PEP-1-SOD and Tat-SOD fusion proteins into neuronal and insulin-producing cells, respectively, was not affected by paraformaldehyde fixation (21,23).…”

“…By using this protein transduction technology, we have previously reported on the efficient transduction of various fusion proteins into mammalian cells and animal tissues. The transduced fusion proteins markedly protected cells and tissues against reactive oxygen species (20)(21)(22)(23).…”

Human brain pyridoxal-5'-phosphate phosphatase (PLPP): protein transduction of PEP-1-PLPP into PC12 cells

“…By using this protein transduction technology, we have reported how various fusion proteins were efficiently transduced into mammalian cells and animal tissues. These transduced fusion proteins markedly protected cells and tissues (21)(22)(23)(24).…”