HIV-1 viral load monitoring: an opportunity to reinforce treatment adherence in a resource-limited setting in Thailand

Viral suppression after 12 months of antiretroviral therapy in low- and middle-income countries: a systematic review

“…A second test is particularly likely to increase the percentage of patients who are virologically suppressed if an intervention to improve adherence to ART occurs after an initial detectable viral load, in a strategy that is recommended by WHO 2 and already followed in several LMICs. 33,77,78 Given that the overwhelming majority of reported outcomes are based on a single viral load measurement per patient, efforts to understand and summarize virological outcomes in LMICs should also be based on a single test result for each patient.…”

Diagnosis and management of antiretroviral-therapy failure in resource-limited settings in sub-Saharan Africa: challenges and perspectives

“…14,47 Thus, widespread availability of a viral-load test might help to conserve fi rst-line regimens and might have a preventive dimension in ART failure. In the development of a POC viral-load test, clear guidance will be needed on the viral-load threshold around which action is taken, the frequency of testing, when to repeat the test if the viral load is high, and when to switch therapies.…”

Antiretroviral therapy for HIV prevention: many concerns and challenges, but are there ways forward in sub-Saharan Africa?

“…A point-of-care viral load test would be an indispensable tool for monitoring adherence and effectiveness. 23 Please cite this article in press as: Zachariah …”