HIV and SARS-CoV-2 Coinfection in A Term Pregnancy

Abstract

The novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the cause of the clinical syndrome COVID-19. Data on SARS-CoV-2 infection in pregnant women is rapidly accumulating and will help improve clinical guidelines for treatment. It is currently unknown if infection with human immunodeficiency virus (HIV) predisposes pregnant women to serious illness from SARS-CoV-2 infection. The greatest risk factors for pre-disposing patients with HIV to de-novo virulent viral infections includes non-adherence to combined antiretroviral therapy (cART) (Center for Disease Control and Prevention, 2020). We present the clinical course, treatment and outcome of a pregnant patient co-infected with HIV and SARS-CoV-2. We document an uncomplicated, full term delivery and highlight the adherence of cART in favorable outcome of pregnancy with SARS-CoV-2 and HIV coinfection.

HIV and SARS-CoV-2 Coinfection in Pregnancy: Case Report

“…To date multiple studies outlining the management of COVID-19 disease during pregnancy have been released. But there have been a few reports regarding the outcomes of mothers co-infected with SARS-CoV-2 and HIV [13]. A study in South Africa reported that pregnant women were associated with severe illness and a significant risk of maternal death in women with high-risk pregnancies including HIV.…”