2024
DOI: 10.7759/cureus.53431
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HIV-Encoded Gene Therapy as Anti-cancer Therapeutics: A Narrative Review

Pachamuthu Balakrishnan,
Sankar Sathish,
Shanmugam Saravanan

Abstract: Recently, there has been interest in using viruses as cancer treatments. Oncolytic virology was founded by scientists who noticed that viruses might preferentially lyse cancer cells over healthy ones. Oncolytic virotherapy has similar obstacles as other treatment approaches, gaining entry into the specific tumour cell, encountering antiviral immune responses, off-target infection and many other unfavourable circumstances in the tumour microenvironment, and a lack of unique therapeutic and predictive biomarkers… Show more

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