This report describes characteristics of HIV test data for men who have sex with men (MSM) tested in 2007 through programs funded by the Centers for Disease Control and Prevention (CDC). HIV test-level data of MSM submitted by 29 health departments were analyzed to explore test characteristics among all tests, first-time tests, and repeat tests. Characteristics significantly associated with HIV-positive results among first-time tests were identified through logistic regression. Of the 129,893 tests conducted, 18% were first-time tests and 82% were repeat tests. HIV positivity among firsttime tests was 4.1% and 3.7% among repeat tests. Among first-time tests, 46% of tests were among White MSM and 48% of HIV-positive test results were among African Americans. An HIV-positive test among first-time tests was strongly associated with being African American, being 40-49 years old, and testing in the southern United States. Race/ethnicity differences exist among MSM testing at CDC-funded sites. African American MSM accounted for the greatest proportion of HIV-positive results but White MSM represented the greatest proportion of tests conducted. HIV prevention strategies that include CDC-funded testing for MSM should increase targeting of African Americans.Men who have sex with men (MSM) bear the greatest burden of HIV infection in the United States. In 2009, male-to-male sexual contact accounted for 23,846 (75%) of the 31,872 estimated new diagnoses among males in 40 states with confidential, name-based HIV reporting (CDC, 2009a). In a meta-analysis of data on same-sex behavior collected from nationally representative samples of men, the Centers for Disease Control and Prevention (CDC) estimated the rate of new HIV diagnoses among MSM to be more than 44 times that of other men and more than 40 times that of women (Purcell et al., 2010). These analyses were based on new estimates of the size of the U.S. population of MSM-according to CDC estimates, 4% of U.S. males had sex with other males in the last 5 years.HIV incidence surveillance data have indicated new infections for all risk groups (MSM, heterosexuals, injection drug users [IDUs], and MSM/IDUs) peaked in the