Hl-a 1 and 8 in Organ Donors

White, A. C.; Costa, Amanda J Da; Morton, Janet

doi:10.1016/s0140-6736(72)92065-x

Cited by 3 publications

(1 citation statement)

References 7 publications

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“…The HL-A antigen frequency in this group did not differ significantly from a control group in the UK described by Stokes et al (1972). Potential cadaver donors were not included as controls in our study, because the frequency of certain antigens (notably HL-Ai and 8) was considerably lower than that found in the healthy normals (White, da Costa & Morton, 1972).…”

Section: Controlsmentioning

confidence: 57%

The incidence of HL-A antigens in dermatitis herpetiformis

White

Barnetson

Costa

et al. 2006

British Journal of Dermatology

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SUMMARY In dermatitis herpetiformis (DH) there are small intestinal abnormalities similar to those in adult coeliac disease (ACD) and there is evidence of other similarities between the two conditions, including immunological disturbances. Two reports of patients with ACD have shown a distinctive distribution of HL‐A phenotypes, with a high incidence of HL‐Ai and 8. A recent paper has described an increased incidence of HL‐A8 in DH. We report a similar study of patients with DH. Twenty‐one of thirty‐five patients had HL‐A8, an incidence of 60%, as compared to 33% of 175 controls. This difference is significant. The relationship of those patients with HL‐A8 to those with abnormal jejunal biopsies, and also to those with circulating auto‐antibodies, is discussed.

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Section: Controlsmentioning

confidence: 57%