1977
DOI: 10.1159/000251035
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HL-A Antigens in Pustular Psoriasis

Abstract: HL-A typing was performed on 97 patients with pustular psoriasis. HLA-B27 was found increased for the combined three subgroups: localized psoriasis of palms and soles, acrodermatitis continua and generalized pustular psoriasis, who were associated with a high incidence of arthritis. These subgroups have this in common with Reiter’s disease indicating a link between the entities. In persistent palmo-plantar pustulosis an increased incidence of HLA-Bw35 was found. HLA-B13, HLA-B17 and HLA-Bw37 which are found ma… Show more

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Cited by 65 publications
(34 citation statements)
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“…The condition with chronic, localized, sterile pustular and scaly inflammation be ginning acrally on fingers or toes tends to re main localized for months or years. It may, however, occasionally evolve into general ized pustular psoriasis with which it shares the HLA association to B27, as it does with Reiter's disease [7], If the condition persists for months and years the nail plates may be completely destroyed.…”
Section: Discussionmentioning
confidence: 99%
“…The condition with chronic, localized, sterile pustular and scaly inflammation be ginning acrally on fingers or toes tends to re main localized for months or years. It may, however, occasionally evolve into general ized pustular psoriasis with which it shares the HLA association to B27, as it does with Reiter's disease [7], If the condition persists for months and years the nail plates may be completely destroyed.…”
Section: Discussionmentioning
confidence: 99%
“…6 In marked contrast, in psoriasis, HLA-B*27 has only occasionally been reported as significantly but slightly increased. 25,26 The increased frequency of HLA-B*39 in PsA was also detected serologically. 17 Three haplotypes containing B*27 or B*39:01 were significantly increased in frequency in the PsA cohort, 15.6% versus 5.5% in reference controls, but were not increased in the psoriasis cohort (4.7%).…”
Section: Hla Alleles and Psa Susceptibilitymentioning
confidence: 76%
“…[6] reported the increased incidences of Aw 19 and Bw35. Elevated prevalence of Bw35 was later confirmed by Zachariae et al [7], but they did not find the increased incidence of Aw 19. Ward and Barnes [8] demon strated that none of these antigens were increased in fre quency; instead, they found an increased incidence of B8.…”
Section: Discussionmentioning
confidence: 88%