HLA Antigens in Systemic Lupus Erythematosus

Obana, Mitsuo; Mita, Seiji; Kohno, Michinori; Matsuoka, Yasuo; Irimajiri, Shoichiro; Fujimori, Ippei; Fukuda, Junya; Takata, Hajime; Konoeda, Y; Sekiguchi, Susumu

doi:10.2177/jsci.4.68

Cited by 3 publications

(4 citation statements)

References 15 publications

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“…These clinical features might be characteristic of patients with JA and SLE. Among previous reports on Japanese SLE and HLA, 18,19,22 an association between SLE and HLA-B39, DRB1*1501, DRB5*0101, and DQB1*0602 has been found. 22 Because only one out of nine patients with JA and SLE in the present study had HLA-B39, and we did not examined DNA typing of HLA in our patients, we could not compare the previous data 22 with ours.…”

Section: Discussionmentioning

confidence: 88%

“…The incidence of HLA antigens in these nine patients was compared with data obtained from the Japanese population 17 , and from Japanese patients with SLE. 18,19 Statistical analysis was performed by 2 test with Yate's correction.…”

Section: Diagnosis Of Sle and Jaccoud's Arthropathymentioning

confidence: 99%

“…NT, not tested a Ouchterlony (ϩ) higher than that in Japanese SLE patients, although these data 18,19 were based on small-scale studies.…”

Section: Hla Typing (Tables 4 and 5)mentioning

confidence: 99%

“…Phenotype frequency (%) of HLA-A and HLA-B in patients and controls HLA Patients with Japanese patients with SLE Japanese JA and SLE Obana et al18 Kameda et al19 P ϭ 0.011; b P ϭ 0.001; c P ϭ 0.012; d P ϭ 0.044…”

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confidence: 99%

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Clinical and immunological features of systemic lupus erythematosus complicated by Jaccoud's arthropathy

Takeishi¹,

Mimori²,

Suzuki³

2001

Modern Rheumatology

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Section: Discussionmentioning

confidence: 88%

Section: Diagnosis Of Sle and Jaccoud's Arthropathymentioning

confidence: 99%

“…NT, not tested a Ouchterlony (ϩ) higher than that in Japanese SLE patients, although these data 18,19 were based on small-scale studies.…”

Section: Hla Typing (Tables 4 and 5)mentioning

confidence: 99%

mentioning

confidence: 99%

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Clinical and immunological features of systemic lupus erythematosus complicated by Jaccoud's arthropathy

Takeishi¹,

Mimori²,

Suzuki³

2001

Modern Rheumatology

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Neonatal lupus erythematosus in Japan

Kaneko

Tanji

Hasegawa

et al. 1992

Journal of the American Academy of Dermatology

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Clinical and immunological features of systemic lupus erythematosus complicated by Jaccoud's arthropathy

Takeishi

Matsubara

Suzuki

2001

Modern Rheumatology

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This work was undertaken to evaluate clinical and immunological features in patients with systemic lupus erythematosus (SLE) complicated by Jaccoud's arthropathy. Patients diagnosed with SLE between 1985 and 1999, and who met the criteria of Villiaumey et al., were checked for Jaccoud's arthropathy. Clinical features were retrospectively analysed for patients with both diseases. Sjögren's syndrome and human leukocyte antigens (HLA) in these patients were evaluated. Jaccoud's arthropathy was found in 15 (4.4%) of 340 patients with SLE. The mean age at the time of SLE diagnosis was significantly higher in these patients than in our control SLE patients, which was 51.2 ± 13.0 years (n = 15) and 29.6 ± 13.0 years (n = 222) (p = 2.1 × 10(-8)). Sjögren's syndrome was diagnosed according to the European Community Study Group's criteria in 10 (91%) of 11 patients examined. The incidence of HLA-A11 (5/9, 55%) and -B61(40) (5/9, 55%) in patients with Jaccoud's arthropathy was higher in the Japanese population (A11, 17.4%, p < 0.05; B61, 17.5%, p < 0.057. Jaccoud's arthropathy in patients with SLE is associated with Sjögren's syndrome, elderly SLE, HLA-A11, and HLA-B61. These clinical features might be characteristic of patients with Jaccoud's arthropathy and SLE.

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HLA Antigens in Systemic Lupus Erythematosus

Cited by 3 publications

References 15 publications

Clinical and immunological features of systemic lupus erythematosus complicated by Jaccoud's arthropathy

Clinical and immunological features of systemic lupus erythematosus complicated by Jaccoud's arthropathy

Neonatal lupus erythematosus in Japan

Clinical and immunological features of systemic lupus erythematosus complicated by Jaccoud's arthropathy

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