HLA-Bw54 and Glaucomatocyclitic Crisis

Hirose, Shunsuke; Ohno, Shigeaki; Matsuda, Hidehiko

doi:10.1001/archopht.1985.01050120071023

Cited by 37 publications

(22 citation statements)

References 18 publications

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“…It has been recently reported that gene polymorphisms at the HLA-B and HLA-C loci, especially at HLA-C*1402, A*1101-C*1402 and B*5101–C*1402 might predispose to the development of PSS in southern Chinese Han population 9. Consistently, Hirose and his colleagues reported that HLA-Bw54 showed significant association with PSS in a Japanese population 7. High frequencies of HLA- A*11 and B*51 allele are observed in Chinese population 22–25.…”

Section: Discussionmentioning

confidence: 76%

Posner-Schlossman syndrome in Wenzhou, China: a retrospective review study

et al. 2017

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Section: Discussionmentioning

confidence: 76%

Posner-Schlossman syndrome in Wenzhou, China: a retrospective review study

et al. 2017

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“…Its pathogenesis still remains unknown, with suggested possible associations including an immunogenetic factor involving HLA-Bw54,[12] viral infections (HSV and CMV),[1314] gastrointestinal disease, and various allergic factors. [15] The IOP is in the range of 40 – 70 mmHg during an acute attack and usually resolves spontaneously.…”

Section: Major Ocular Inflammations Associated With Secondary Glaucomamentioning

confidence: 99%

Inflammatory glaucoma

et al. 2011

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Glaucoma is seen in about 20% of the patients with uveitis. Anterior uveitis may be acute, subacute, or chronic. The mechanisms by which iridocyclitis leads to obstruction of aqueous outflow include acute, usually reversible forms (e.g., accumulation of inflammatory elements in the intertrabecular spaces, edema of the trabecular lamellae, or angle closure due to ciliary body swelling) and chronic forms (e.g., scar formation or membrane overgrowth in the anterior chamber angle). Careful history and follow-up helps distinguish steroid-induced glaucoma from uveitic glaucoma. Treatment of combined iridocyclitis and glaucoma involves steroidal and nonsteroidal antiinflammatory agents and antiglaucoma drugs. However, glaucoma drugs can often have an unpredictable effect on intraocular pressure (IOP) in the setting of uveitis. Surgical intervention is required in case of medical failure.Method of Literature Search:Literature on the Medline database was searched using the PubMed interface.

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“…Both immunological and infectious etiologies have been considered in the pathogenesis [3,4,5,] .PSS is a rare condition with an uncertain aetiology and no recognised associated systemic conditions. A Japanese study of 22 patients with PSS showed that HLABw54 was positive in nine (41 per cent), 6 implicating a possible CD8 T-cell immunogenetic role. Herpes simplex virus has been detected in the anterior chamber of a small sample of three patients during ocular hypertensive attacks.…”

Section: Discussionmentioning

confidence: 42%