2012
DOI: 10.1186/1756-0500-5-90
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HLA molecules and nasal carriage of Staphylococcus aureus isolated from dialysis and kidney transplant patients at a hospital in Southern Brazil

Abstract: BackgroundHealthy individuals can host Staphylococcus aureus in the nasopharynx, body surface and vagina. Most invasive infections by this bacterium are endogenous, caused by strains spread from the nasopharynx of carriers. S. aureus is a pathogen involved in the etiology of hospital- and community-acquired infections. Transplant and dialysis patients are at risk of colonization or infection by multi-resistant S. aureus. Infection is directly linked to individual immunity, and the major histocompatibility comp… Show more

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Cited by 12 publications
(12 citation statements)
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“…It is possible that the introduction of safer dialysis connections and antibiotic prophylaxis had a greater effect on S. aureus than CNS peritonitis prevention. A high prevalence of S. aureus nasal carriage in our country (33) could explain, at least in part, these contrasting findings.…”
Section: Discussioncontrasting
confidence: 39%
“…It is possible that the introduction of safer dialysis connections and antibiotic prophylaxis had a greater effect on S. aureus than CNS peritonitis prevention. A high prevalence of S. aureus nasal carriage in our country (33) could explain, at least in part, these contrasting findings.…”
Section: Discussioncontrasting
confidence: 39%
“…[5,6] The detection of specific HLA types has proven to be a valuable tool for the diagnosis of some important diseases such as ankylosing spondylitis, inflammatory bowel disease and multiple sclerosis. [7,8] Several emerging studies have described significant correlations between HLA and some renal diseases such as diabetic nephropathy, IgA nephropathy, and glomerulonephritis.…”
mentioning
confidence: 99%
“…Este patógeno pode ser encontrado colonizando 27% dos seres humanos de maneira assintomática (Young, Golubchik et al 2012), e os sítios de maior prevalência são fossas nasais, axilas e períneo (Giarola, Santos et al 2012). Tal agente pode causar diversos processos patológicos, desde mais simples como furúnculo e acne, até mais complexos como sepse, síndrome de choque tóxico, endocardites, pneumonias e infecções associadas com dispositivos intravasculares, corpos estranhos e formação de biofilme (Santos, Santos et al 2007; Hagihara, Umemura et al 2012; Rudkin, Edwards et al 2012).…”
Section: Introductionunclassified