HMU fluorinze mouthwash enhances enamel remineralization: An in vitro study

Abstract

BACKGROUND: Fluoride therapy has long been used extensively to prevent dental caries. Fluoride appears in variety of dental care products such as mouthrinse, dentifrice, gel, etc. HMU fluorinze is the first mouthwash containing fluoride in Vietnam.
 AIM: This research was conducted to evaluate the efficacy of HMU Fluorinze mouthwash on remineralizing enamel in laboratory conditions.
 METHODS: 20 third molars teeth were cleaned and covered with nail polish , except for a 3x3 mm square on their buccal surfaces. These teeth went through two steps: demineralization using Coke and remineralization for 20 days: 1) using standard calcifying solution (control group) and 2) using standard calcifying solution + HMU Fluorinze mouthwash 2 times/day (experimental group). The mineralization index of enamel structure after demineralization and remineralization was assessed by DIAGNOdent pen 2190.
 RESULTS: The mineralization indexes of the control group and experimental group at baseline were 3.65 ± 0.76 and 3.35 ± 0.64, after demineralization were in turn of 21.78 ± 4.48 and 20.25 ± 2.26; and after remineralization were 6.30 ± 1.03 and 3.90 ± 1.24. The different figures between the two groups after remineralization shows statistical significance (p<0.01). Group B using HMU fluorinze mouthwash after 20 days did not differ from the original results (p = 0.272), in contrast with the control group (p<0.01).
 CONCLUSIONS: HMU fluorinze mouthwash has better mineralization effect than standard calcifying solution.

Remineralizing Potential and Antibacterial Effect of Different Mouthwashes on Demineralized Enamel in Acidic challenges: an Invitro Study

“…Zone inhibition test which also called 'Agar Plate's diffusion method' was adopted for this study as it was recorded that this method allow prolonged antibacterial activity of any materials by the direct contact between bacteria and tested material (27,28) . Antimicrobial assessment test revealed the at 24 and 48 hours recorded statistically significant reduction the streptococcus mutans especially for the s Listerine mouthwashes followed by DG wash and finally antiradical saliva group which may be explained by the synergetic effect that obtained by combination of essential oils (5,9,29) with fluoride (1,2,3,15) as both materials was documented that it has an potent antibacterial effect. This result was in coordination with the result of Kato et al, 1999 who reported a decrease of not only the number of microorganisms and decrease in plaque induced by mouth washing in response to Listerine.…”

“…Results of inter and intragroup comparisons for bacterial inhibition zones are presented in table (2). Results showed that for both intervals, there was a significant difference between tested groups with Listerine TP and Listerine GP having significantly higher values than other groups and with DG wash having significantly higher value than saliva group (p>0.05).…”

“…Fluoride available in different forms of dental care products such as mouth washes, tooth pastes, gels, etc. Usually, patients with high caries index were advised to use a fluoride containing mouthwash and brush-on gel at home, as an adjunct to brushing with a fluoride tooth paste (2) . Besides the caries prevention role of fluoride, it also has a great impact in enhancing the re-mineralization of demineralized enamel that explain his effect in reducing the progress of initial carious enamel lesions (3) .…”