Hoarseness in children: The role of laryngopharyngeal reflux

Block, Bradley B.; Brodsky, Linda

doi:10.1016/j.ijporl.2006.10.029

Cited by 53 publications

(25 citation statements)

References 15 publications

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“…Children aged 0 -3 years were commonly affected which is in consonance with earlier studies in sub-Saharan Africa [4]. This is because children in this age group are very inquisitive and still exploring objects in their environment placing them in their mouth more frequently [11]- [13]. This underscores the need for awareness and close monitoring of these children by their parents or caregivers.…”

Section: Discussionsupporting

confidence: 83%

Clinical Analysis of Hoarseness in Children as Seen in Otorhinolaryngology Department of a Tertiary Health Institution in North-West, Nigeria

Daniel¹,

Stanley²

2016

OJPed

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Normal phonation is produced in the larynx by the blast of pulmonic air stream that vibrates the vocal cords. Hoarseness reflects changes in the structure or function of the vocal cords. Objective: This is to describe the clinical profile of hoarseness in children and aetiological factors in a tertiary health institution. Methodology: This is a retrospective eight-year (2006-2013) study of clinical records of patients with hoarseness as their main symptom seen in the ENT department of the Usmanu Danfodiyo University Teaching Hospital Sokoto. Results: Fifty-two children with hoarseness were studied. Thirty three (63.5%) were males, while 19 (36.5) were female with a male: female ratio of 1.7:1. The age range was 1 -13 years with a mean age of 5.1 years. Age group 4 -7 years (38.5%) were observed to be more affected with duration of hoarseness ranging from 1 day to 5 years. RRP 23 (44.2%) was the most common aetiology of hoarseness followed by foreign body 15 (28.8%) and Acute Laryngeal infections 9 (17.3%). Tracheostomy was done in 29 (55.8%) of patients. Two patients died post operatively due to improper tracheostomy tube care in the ward. Conclusion: With delayed presentation and its attendant grave sequelae, it has become imperative that persistent hoarseness in children lasting more than three weeks should be endoscopically evaluated by an otorhinolaryngologist.

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Section: Discussionsupporting

confidence: 83%

Clinical Analysis of Hoarseness in Children as Seen in Otorhinolaryngology Department of a Tertiary Health Institution in North-West, Nigeria

Daniel¹,

Stanley²

2016

OJPed

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“…Block et al performed a retrospective analysis including 295 children aged 7.2 ± 4.3 years with hoarseness persisting for more than 3 years. In 36% of them, LPR symptoms occurred during laryngological examination [6]. Although the precise prevalence of reflux in children is not known, it is estimated that 1 in 5 children may present with the symptoms of reflux [7].…”

Section: Discussionmentioning

confidence: 99%

Chronic Cough as a Symptom of Laryngopharyngeal Reflux—Two Case Reports

Kopka¹,

Małecka²,

Stelmach³

2015

Advances in Respiratory Medicine

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Laryngopharyngeal reflux (LPR ) is a complex of symptoms caused by the backflow of gastric contents into the larynx, pharynx, nasopharynx, sinuses and even to the middle ear space.The symptomatology of LPR includes: chronic cough, hoarseness, throat clearing, laryngitis, "globus pharyngeus", swallowing disturbances, postnasal drip, "fetor ex ore". In the article, the authors present two boys with chronic cough, in one of them the asthma was suspected and antiasthmatic treatment was administrated; in our patients according to the 24-hour pharyngeal pH-metry LPR was diagnosed. The aim of this study was to emphasise that pediatricians should be able to recognise symptoms of LPR. The appropriate diagnosis and treatment leads the symptoms to subside.

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“…Symptoms of GERD may include: regurgitation, persistent vomiting, anorexia/feeding refusal, hypersalivation, arching, irritability, persistent crying, abdominal and epigastric pain, heartburn, chest 3,4 Sandifer's syndrome (head turning episodes to lengthen the esophagus, repetitive stretching and arching, which gives the appearance of seizure/dystonia), 5 dental erosion, 6 and many other extra-intestinal manifestations, mainly respiratory symptoms such as stridor, recurrent wheezing, cough, chronic laryngitis, hoarseness, asthma. [7][8][9] In the more severe forms of GERD esophageal complications like erosive or ulcerative esophagitis, 10 hemorrhage, stricture, Barrett's esophagus 11,12 may be diagnosed. The main aims of the treatment of GERD in children are to relieve symptoms, promote normal growth and prevent the afore-mentioned complications.…”

Section: Introductionmentioning

confidence: 99%

Delayed-release oral suspension of omeprazole for the treatment of erosive esophagitis and gastroesophageal reflux disease in pediatric patients: a review

Monzani¹,

Oderda²

2010

CEG

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Abstract:Omeprazole is a proton-pump inhibitor indicated for gastroesophageal reflux disease and erosive esophagitis treatment in children. The aim of this review was to evaluate the efficacy of delayed-release oral suspension of omeprazole in childhood esophagitis, in terms of symptom relief, reduction in reflux index and/or intragastric acidity, and endoscopic and/or histological healing. We systematically searched PubMed, Cochrane and EMBASE (1990 to 2009) and identified 59 potentially relevant articles, but only 12 articles were suitable to be included in our analysis. All the studies evaluated symptom relief and reported a median relief rate of 80.4% (range 35%-100%). Five studies reported a significant reduction of the esophageal reflux index within normal limits (7%) in all children, and 4 studies a significant reduction of intra-gastric acidity. The endoscopic healing rate, reported by 9 studies, was 84% after 8-week treatment and 95% after 12-week treatment, the latter being significantly higher than the histological healing rate (49%). In conclusion, omeprazole given at a dose ranging from 0.3 to 3.5 mg/kg once daily (median 1 mg/kg once daily) for at least 12 weeks is highly effective in childhood esophagitis.

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Hoarseness in children: The role of laryngopharyngeal reflux

Cited by 53 publications

References 15 publications

Clinical Analysis of Hoarseness in Children as Seen in Otorhinolaryngology Department of a Tertiary Health Institution in North-West, Nigeria

Clinical Analysis of Hoarseness in Children as Seen in Otorhinolaryngology Department of a Tertiary Health Institution in North-West, Nigeria

Chronic Cough as a Symptom of Laryngopharyngeal Reflux—Two Case Reports

Delayed-release oral suspension of omeprazole for the treatment of erosive esophagitis and gastroesophageal reflux disease in pediatric patients: a review

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