Hodgkin’s lymphoma coexisting with liver failure secondary to acute on chronic hepatitis B

Palta, Renee; McClune, Amy; Esrason, Karl T.

doi:10.12998/wjcc.v1.i1.37

Cited by 5 publications

(2 citation statements)

References 15 publications

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“…One of the most common types of B cell lymphoma is diffuse large B cell lymphoma (DLBCL). DLBCL is often treated with chemotherapy [7,8], radiation therapy, or both [9][10][11].…”

Section: Discussionmentioning

confidence: 99%

Case Study of Acute Liver Failure Due to Large B-Cell Lymphoma

Prakash¹

2022

Fut J. Pharm & H. Sci

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This case study is about a 72 yrs elderly woman as for acute liver failed due to huge b-cell lymphoma diffusion. The patient was diagnosed with the disease in the past and was on treatment for it. However, she started showing symptoms of fatigue and jaundice which led to hospitalization. The study looks at her medical history and current condition as well as how her disease has progressed over time. It also discusses the various treatments that have been tried so far and their effects on her. A CT scan indicated a huge B-cell lymphoma diffusely involving the liver. The patient underwent an emergency laparotomy and resection of the liver lesion because her condition was deteriorating rapidly. The woman had an enlarged liver (10 cm) with a nodular surface and diffusely increased attenuation on CT scan. She also had a gallbladder wall thickening on ultrasound examination. She has been hospitalized for the further assessment as well as organization of her acute liver fail due to huge B-cell lymphoma dispersion. The seventy two yrs elderly women acute liver problem due to huge B-cell lymphoma dispersion has been hospitalized for such a liver transplant. The patient has been given a diagnosis with huge B-cell lymphoma, that have distributed to her liver. The patients condition worsened incredibly quickly but she was admitted for a liver transplant. Acute liver failure can be caused by many different conditions, including poisoning, drug-induced hepatitis, viral hepatitis, alcoholic hepatitis, autoimmune hepatitis, and hepatic malignancies. Acute liver failure is usually reversible if it is caused by an identifiable cause and if that cause can be treated.

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“…One of the most common types of B cell lymphoma is diffuse large B cell lymphoma (DLBCL). DLBCL is often treated with chemotherapy [7,8], radiation therapy, or both [9][10][11].…”

Section: Discussionmentioning

confidence: 99%

Case Study of Acute Liver Failure Due to Large B-Cell Lymphoma

Prakash¹

2022

Fut J. Pharm & H. Sci

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“…The mechanism of liver failure is likely from cholangitis, ischemia, and necrotic injury following infiltration of small hepatic bile ducts. 3,4 Microscopy of liver biopsy sections demonstrated liver parenchyma partially obliterated by an atypical lymphoid infiltrate. These lymphoid cells were mostly small to medium in size with irregular nuclear contours and mature chromatin features.…”

Section: Discussionmentioning

confidence: 99%

Primary Hepatic Follicular Lymphoma Presenting as Sub-acute Liver Failure: A Case Report and Review of the Literature

Williams

Akhondi

Khan

2019

Clin Med�Insights�Pathol

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Sub-acute liver failure is a term that describes the relatively sudden loss of liver function, usually >21 days and <26 weeks, with impaired synthetic function and associated encephalopathy in a person with no pre-existing liver disease or cirrhosis. It is commonly caused by viruses and drugs, less so by malignancy. Our patient is a 71-year-old Japanese man who presented with signs of sub-acute liver failure. A subsequent liver biopsy demonstrated involvement by B-cell non-Hodgkin lymphoma. Evaluation of the bone marrow demonstrated significant marrow involvement by B-cell lymphoma. The fluorescence in situ hybridization (FISH) returned positive for t(14; 18). Noted was the patient’s clinical presentation of cholestasis secondary to hepatic lymphoma with no evidence of lymphadenopathy or peripheralized lymphoma. Given the disease distribution, the overall findings are consistent with primary hepatic follicular lymphoma as described in few case reports and small case series in the literature.

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