For Besov spaces B s p,r (R) with s > max{2 + 1 p , 5 2 }, p ∈ (1, ∞] and r ∈ [1, ∞), it is proved that the data-to-solution map for the FORQ equation is not uniformly continuous from B s p,r (R) to C([0, T ]; B s p,r (R)). The proof of non-uniform dependence is based on approximate solutions and the Littlewood-Paley decomposition.