Holding the Patient

Williams, Gini

doi:10.1111/j.1749-6632.2001.tb11378.x

Cited by 11 publications

(3 citation statements)

References 15 publications

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“…, 2012). Moreover, Williams (2001) put forward that WPO plays the role of an interpersonal stressor, resulting in stress. This argument is also supported by the COR theory, which posits that stress occurs when key resources are threatened or actually lost (Hobfoll et al.…”

Section: Hypotheses Developmentmentioning

confidence: 99%

“…Previously, scholars have shown that ostracism is related to negative affect (Williams et al, 2002), depression, anxiety, frustration (Colligan and Higgins, 2006) and emotional exhaustion (Wu et al, 2012). Moreover, Williams (2001) put forward that WPO plays the role of an interpersonal stressor, resulting in stress. This argument is also supported by the COR theory, which posits that stress occurs when key resources are threatened or actually lost (Hobfoll et al, 2018, p. 104).…”

Section: Hypotheses Development 21 Direct Relationshipmentioning

confidence: 99%

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How ostracism jeopardizes customers' interests at restaurants: a study in context of COVID-19

Sarwar

Abdullah

Imran

et al. 2022

JABES

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PurposeWith theoretical underpinnings in the conservation of resources theory, this research aims at understanding the link between workplace ostracism (WPO) and its effects on customers' interests in the context of COVID-19, with the mediation of stress and moderation of self-efficacy (SE).Design/methodology/approachThe study followed a time-lagged design. A sample of 217 frontline employees working in the food sector of southern Punjab, Pakistan responded to the study questions using survey method with structured questionnaires. A Statistical Package for the Social Sciences (SPSS) tool was utilized for data analysis with bootstrapping and PROCESS macro.FindingsThe findings show that an important mechanism by which ostracism translates into customer service sabotage (CSS) is the increase in perceived stress levels of the employees. Additionally, SE was found to be an important personal resource that acts as a moderator in the said relationship.Practical implicationsEmployees with high SE sense less workplace stress even during a pandemic. Leadership should consider the stress-alleviating effect of SE for lessening the damaging influence of WPO on customers.Originality/valueThe study fills an important empirical gap in the context of the COVID-19 pandemic, by showing that due to resource loss perceived by employees while being targeted by ostracism, they may decide to transfer their frustration towards organizational customers by sabotaging their service experience.

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Section: Hypotheses Developmentmentioning

confidence: 99%

Section: Hypotheses Development 21 Direct Relationshipmentioning

confidence: 99%

How ostracism jeopardizes customers' interests at restaurants: a study in context of COVID-19

Sarwar

Abdullah

Imran

et al. 2022

JABES

View full text Add to dashboard Cite

show abstract

“…According to psychological research studies, exclusion feelings and physical pain activates the same areas at the brain (Eisenberger, Lieberman & Williams, 2003). Workplace exclusion threatens belongingness, self-esteem, meaningfulness, and individual control (Williams, 2001(Williams, & 2007 and affects employees' psychology and behavior (Bedi & Skowronski, 2014). Workplace exclusion also diminishes cooperation and synergy among employees (Özer & Günlük 2010).…”

Section: Workplace Exclusionmentioning

confidence: 99%

Linking Workplace Exclusion with Employees’ Intention to Leave with the Mediating and Moderating Role of Self-esteem

Ertop

Erdoğan

2023

Optimum Ekonomi Ve Yönetim Bilimleri Dergisi

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This study aims to investigate the relationship between workplace exclusion and intention to leave with the mediating and moderating role of self-esteem. Data was collected from 200 white-collar employees working in durable consumer goods industry in Türkiye. Results showed that workplace exclusion is positively related to intention to leave and negatively related to self-esteem. Self-esteem is negatively related to intention to leave. Additionally, it was found that self-esteem has not a mediation function. Self-esteem plays a significant role as a function of moderation between workplace exclusion and intention to leave. Practice of our findings and implications for the research are discussed in this study.

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Highly oxidized albumin is mainly cleared by mouse liver sinusoidal endothelial cells via the receptors stabilin-1 and -2

Holte

Kruse

Simón-Santamaría

et al. 2023

Preprint

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Background: Oxidized albumin (oxHSA) is elevated in several pathological conditions, especially those involving the liver, such as decompensated cirrhosis, acute on chronic liver failure and liver mediated renal failure. Patient derived oxidized albumin was previously shown to be an inflammatory mediator in cultured endothelial cells and leukocytes. The removal from circulation of oxidized albumins is therefore essential for maintenance of homeostasis. Normal serum levels of oxidized albumin are low, implying it is constantly eliminated. Liver sinusoidal endothelial cells (LSEC) are prominent scavenger cells in the body, specializing in the removal of macromolecules e.g. hyaluronan, denatured collagen, modified albumins, bacterial endotoxin (LPS) and oxidized lipoprotein. Given that oxidized albumin is mainly cleared by the liver, we hypothesize the LSEC are the site of uptake in the liver. Furthermore the stabilins -1 and -2 are the most prominent candidates for oxHSA uptake receptors, given their expression pattern and uptake of other ligands. Methods: In vivo biodistribution, hepatocellular distribution and in vitro uptake studies on isolated liver cell populations or receptor expressing cell lines. Results: In vivo oxHSA was cleared rapidly (t1/2 <90seconds) by the liver (47% of uptake) and distributed to mainly the LSEC. In in vitro studies LSEC endocytosed oxHSA much more than other cell populations isolated from the liver. Furthermore, it was shown that the uptake was mediated by the stabilins, by inhibiting uptake in LSEC with other stabilin ligands and showing uptake in HEK cells overexpressing stabilin- 1 or 2. oxHSA also inhibited the uptake of other stabilin ligands. Conclusions: LSEC and their stabilins are vital for the clearance of oxidized albumin, and therefore play a pivotal role in maintaining homeostasis.

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Holding the Patient

Cited by 11 publications

References 15 publications

How ostracism jeopardizes customers' interests at restaurants: a study in context of COVID-19

How ostracism jeopardizes customers' interests at restaurants: a study in context of COVID-19

Linking Workplace Exclusion with Employees’ Intention to Leave with the Mediating and Moderating Role of Self-esteem

Highly oxidized albumin is mainly cleared by mouse liver sinusoidal endothelial cells via the receptors stabilin-1 and -2

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