Hollow-Bone-Graft Dynamic Hip Screw Can Fix and Promote Bone Union after Femoral Neck Fracture: an Experimental Research

Shen, Jiazuo; Yao, Jian-Fei; Lin, Dasheng; Lian, Kun; Ding, Zhenqi; Lin, Bin; Guo, Zhouyi; Zhang, Minghua; Li, Qiang; Li, Lin; Peng, Qi

doi:10.7150/ijms.4567

Cited by 4 publications

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“…It was shown in previous study that the Hb-DHS promotes femoral neck bone union, stimulates trabecular bone formation, increases bone mineral density with reliable internal fixation in an experimental study. 4 Thus nonunion and femoral head avascular necrosis could be greatly decreased. The purpose of this study was to evaluate the efficacy and safety of the Hb-DHS with autogenous bone and bone morphogenetic protein 2 (BMP-2) composite materials grafting for the treatment of the neglected femoral neck fractures in young adults.…”

Section: Introductionmentioning

confidence: 99%

Treatment of neglected femoral neck fractures using the modified dynamic hip screw with autogenous bone and bone morphogenetic protein-2 composite materials grafting

Lin¹,

Zuo²,

Li³

et al. 2015

IJOO

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Background:The neglected femoral neck fracture is one where there has been a delay of more than 30 days to seek medical help from the time of the original injury. Salvage procedures, such as osteotomy and other treatment options such as vascularized and nonvascularized bone grafts have high failure rates and arthroplasty procedures are not ideal, given the patient's young age and higher levels of activity. We designed a hollow bone graft dynamic hip screw (Hb-DHS) (modified DHS, Hb-DHS) for use in neglected femoral neck fractures. This study evaluates the efficacy and safety of the modified dynamic hip screw (DHS) with autogenous bone and bone morphogenetic protein 2 (BMP-2) composite materials grafting for the treatment of the neglected femoral neck fractures.Materials and Methods:A prospective study was carried out in twenty patients of neglected femoral neck fractures treated with the modified DHS with autogenous bone and BMP-2 composite materials grafting between July 2007 and February 2010. There were 14 men and 6 women with a mean age of 29.6 years (range 19–42 years). The mean time from injury to surgery was 9.7 weeks (range 6–16 weeks). The operation time, intraoperative blood loss, fracture healing time, Harris scoring for hip function and complications were recorded to evaluate treatment effects.Results:The mean operation time was 75.8 min (range 55–100 min) with mean intraoperative blood loss volume of 105 mL (range 70–220 mL). The mean time to union was 17 weeks (range 12–24 weeks). One patient did not achieve union, and two patients had avascular necrosis of the femoral head. This patient with nonunion underwent intertrochanteric osteotomy. In patients with avascular necrosis one required total hip arthroplasty, the other did not require intervention at the last followup. A total of 14 patients (70%) had excellent results, 2 (10%) had good, 1 (5%) had moderate and 3 (15%) had poor results.Conclusion:The modified DHS with autogenous bone and BMP-2 composite materials grafting for the treatment of neglected femoral neck fractures waseffective and had less complications.

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Section: Introductionmentioning

confidence: 99%