Hollow carbon nanospheres embedded with stoichiometric γ-Fe₂O₃ and GdPO₄: tuning the nanospheres for in vitro and in vivo size effect evaluation

Abstract

The size modulation of hollow carbon nanospheres (HCS) has attracted great interest in the contexts of cellular uptake, drug delivery and bioimaging. In this study, a facile fabrication method was...

A Review of Advanced Multifunctional Magnetic Nanostructures for Cancer Diagnosis and Therapy Integrated into an Artificial Intelligence Approach

“…Graphitic carbon coating on FeCo prevents FeCo leaching and makes the magnetic nanoparticle more stable, whereas poly(ethylene glycol) coating on functionalized MNP surfaces enhances particle stability, dispersibility, and biocompatibility. Moreover, several hollow carbon nanospheres embedded with γ-Fe 2 O 3 and GdPO 4 (Fe–Gd/HCS), dual-Fe nanoparticles embedded within synchronized carbon nanostructures, and co-functionalized mesoporous carbon spheres with γ-Fe 2 O 3 and GdPO 4 have also been successfully developed and applied for the integration of magnetic resonance imaging and drug delivery [ 73 , 74 , 75 , 76 , 77 ]. Multiwall carbon nanotubes (MWCN) with magneto-fluorescent carbon quantum dots resulted in synergistic effects toward dual-modal targeted imaging [ 78 ].…”

Mesoporous carbon hemispheres integrated with Fe–Gd nanoparticles for potential MR/PA imaging-guided photothermal therapy

“…38 We demonstrated its compatibility with various morphologies ranging from FDU-15, FDU-16 to mesoporous carbon nanosphere and hollow carbon nanosphere and revealed the size-dependent magnetic resonance imaging (MRI) performances as well as the in vitro endocytosis and in vivo behaviors. 38–42 Despite these achievements, whether the asymmetric mesoporous carbon hemisphere is superior to the corresponding spherical one for photothermal conversion and its theranostic capability are still pending issues.…”