Holmium Laser Enucleation of the Prostate: A Modified Enucleation Technique and Initial Results

Gong, Yong-Guang; He, Dalin; Wang, Mingzhu; Li, Xudong; Zhu, Guodong; Zhi-hu, Zheng; Du, Yifan; Chang, Luke S.; Nan, Xunyi

doi:10.1016/j.juro.2011.11.093

Cited by 50 publications

(28 citation statements)

References 22 publications

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“…As illustrated by several typical studies of HoLEP, there was no significant correlation between stress UI and these factors (linear regression analysis prostate volume p ϭ 0.19, PVR p ϭ 0.35 and tissue weight p ϭ 0.71; table 4). [14][15][16][17][18][19][20][21][22][23] Our results also coincide with the results analysis in table 4. Thus, we believe surgical technique is an important factor in the risk of stress UI.…”

Section: Discussionsupporting

confidence: 91%

A Prospective, Randomized Clinical Trial Comparing Plasmakinetic Resection of the Prostate with Holmium Laser Enucleation of the Prostate Based on a 2-Year Followup

Chen

Wang

et al. 2013

Journal of Urology

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Plasmakinetic resection and holmium laser enucleation of the prostate are effective and safe treatments for benign prostatic hyperplasia. Holmium laser enucleation of the prostate can be applied to prostates of all sizes, and involves less risk of hemorrhage, decreased bladder irrigation and catheter times, as well as reduced hospital stay. Thus, we believe holmium laser enucleation of the prostate should be proposed as a potential new gold standard surgical therapy instead of transurethral resection of the prostate for patients with benign prostatic hyperplasia.

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Section: Discussionsupporting

confidence: 91%

A Prospective, Randomized Clinical Trial Comparing Plasmakinetic Resection of the Prostate with Holmium Laser Enucleation of the Prostate Based on a 2-Year Followup

Chen

Wang

et al. 2013

Journal of Urology

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“…Over the years, many modifications have been developed, and the original surgical technique has evolved considerably [222324]. The en bloc nucleation is a method of enucleating the three prostatic lobes from the prostatic capsule as a whole lump, and several en bloc enucleation methods have emerged worldwide since 2010 [2526272829].…”

Section: Historical Considerationsmentioning

confidence: 99%

Current surgical techniques of enucleation in holmium laser enucleation of the prostate

2019

Investig Clin Urol

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Holmium laser enucleation of the prostate (HoLEP) has been accepted as the most efficient method of transurethral surgery for benign prostatic hyperplasia. The originally developed three-lobe technique has popularized this surgery; this method is based on three longitudinal incisions, by which the median lobe is removed, and subsequently, both lateral lobes are enucleated. To maintain a consistent surgical plane and to minimize sphincteric damage, the traditional three-lobe technique is continuously being refined and evolving. A few modifications of the original technique have been developed, and several en bloc enucleation methods have been introduced. However, more clinical evidence is required to show the superiority of newer techniques over the original three-lobe technique in terms of efficacy and long-term side effects. To date, none of the newer techniques have been accepted as a standard technique for HoLEP.

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“…Normally, stress incontinence resolves during the first 6 to 12 months. In a study by Chen and colleagues, 19 of 140 patients in the HoLEP group, SUI occurred in 13 (9.2%) patients, which resolved in all the patients by the 6th postoperative month; while in Gong and colleagues, 20 3 cases of SUI resolved by the 3rd postoperative month.…”

Section: Discussionmentioning

confidence: 95%

Long-Term Outcomes of Holmium Laser Enucleation of the Prostate: A 5-Year Single-Center Experience

Enikeev

Taratkin

Morozov

et al. 2020

Journal of Endourology

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Objective: To analyze the long-term efficacy and safety of holmium laser enucleation of the prostate (HoLEP) for benign prostatic hyperplasia. Materials and Methods: A total of 127 patients who underwent HoLEP at our institution between 2013 and 2015 were included. Patients were observed for 5 years postoperatively. We evaluated the length of the surgery, the mass of the removed tissue, prostate-specific antigen level, the maximal flow rate (Qmax), postvoid residual (PVR), the length of catheterization and hospitalization, and the International Prostate Symptom Score (IPSS) and IPSS quality of life (QoL) at each clinic visit. Results: PVR, Qmax, IPSS, and QoL all improved significantly immediately after the operation (p < 0.001). By the end of the 5th postoperative year, all the parameters showed a statistically meaningful decline: Qmax reduced by 5.8 mL/s (22.6%) and IPSS by 1.4 points (29.1%). Around 8.6% of the patients continued therapy with a-blockers. There were no differences in efficacy by the age of the patients or the volume of the prostate. Longterm complications and need for repeat operations were not affected by the volume of the prostate or patient age. Conclusions: The improvement of PVR, Qmax, IPSS, and QoL score seen in the early postoperative period after performing HoLEP remains evident at 5 years postoperatively. Long-term complications and the need for reoperation do not depend on the age of the patient or on the initial volume of the prostate.

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Holmium Laser Enucleation of the Prostate: A Modified Enucleation Technique and Initial Results

Abstract: The modified holmium laser enucleation of the prostate technique is effective and safe when treating benign prostatic hyperplasia.

Cited by 50 publications

References 22 publications

A Prospective, Randomized Clinical Trial Comparing Plasmakinetic Resection of the Prostate with Holmium Laser Enucleation of the Prostate Based on a 2-Year Followup

A Prospective, Randomized Clinical Trial Comparing Plasmakinetic Resection of the Prostate with Holmium Laser Enucleation of the Prostate Based on a 2-Year Followup

Current surgical techniques of enucleation in holmium laser enucleation of the prostate

Long-Term Outcomes of Holmium Laser Enucleation of the Prostate: A 5-Year Single-Center Experience

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