E 8 4 5What ' s known on the subject? and What does the study add? The major advantage of holmium laser enucleation of the prostate (HoLEP) depends on the ability to use the native anatomical plane between the prostate adenoma and surgical capsule, peeling each prostatic lobe from the capsule. HoLEP is associated with less catheterisation time, hospital stay and blood loss than transurethral resection of the prostate (TURP) or open prostatectomy. Urodynamic relief of obstruction has been reported to be better with HoLEP than TURP. However, surgical treatment of recurrent prostatic obstruction after previous transurethral surgery for symptomatic benign prostatic hyperplasia is more challenging because of loss of anatomical landmarks resulting in either incomplete removal or incontinence.HoLEP for recurrent symptoms due to residual or re-growing prostatic adenoma seems to be as safe, feasible and effi cient as HoLEP for de novo cases. The surgical plane between the adenoma and the surgical capsule was still accessible resulting in a durable long-term outcome with minimal side-effects. Previous transurethral prostatic surgery is not a contraindication for HoLEP.
OBJECTIVE• To assess the technical feasibility, functional outcome and morbidity of holmium laser enucleation of the prostate (HoLEP) for symptomatic benign prostatic hyperplasia (BPH) in patients with previous transurethral prostate surgery. ' Redo ' surgery for recurrent or residual BPH poses a technical challenge with uncertain outcome as a result of disturbed anatomical landmarks with no clear surgical limits.
PATIENTS AND METHODS• We retrospectively reviewed 1054 patients who underwent HoLEP for symptomatic BPH.• Patients were stratifi ed into two groups, group-I with no previous prostate surgery or primary-HoLEP (978 patients) and group-II with history of previous prostate surgery or secondary-HoLEP (76).• All patients ' variables as well as follow-up data were assessed and compared.
RESULTS• There were no signifi cant differences in baseline criteria between the two groups ( P > 0.05).• In group-II, HoLEP was done after a median (range) of 66 (13 -121) months from previous prostate surgeries, including transurethral resection of the prostate (48 patients), HoLEP (eight), transurethral incision of the prostate (nine), photoselective vaporization of the prostate (four) and other procedures (seven).• In both groups, routine HoLEP technique was adopted, the plane of enucleation could be identifi ed without extra diffi culty. However, more energy per gram of prostate tissue was needed in group-II ( P < 0.05).• Operative auxiliary procedures were indicated in 1.9% of group-I, and 1.3% of group-II ( P > 0.05). There were no operative complications or blood transfusion in group-II. The mean hospital stay and catheter time was similar in both groups. Early and late postoperative complications were not statistically different ( P > 0.05).• At 1 month the mean maximum urinary fl ow rate (Q max ) was 22.3 and 18.8 mL/s, postvoid residual urine volume (PVR) was 4...