Holmium Laser Treatment of Genital Warts: an Observational Study of 1500 Cases

Yang, Chonglin; Liu, Shengxiu; Liu, Jiangbo; Wang, Zhongying; Luo, Dan; Zhang, Guolong; Zhang, Xuejun; Yang, Sen

doi:10.2340/00015555-0354

Cited by 14 publications

(15 citation statements)

References 9 publications

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“…Holmium laser treatment is one of the effective methods for the treatment of genital warts . The treatment of giant genital warts usually requires 3 to 4 weeks of recovery time after holmium laser treatment.…”

Section: Discussionmentioning

confidence: 99%

Cold atmospheric plasma promotes different types of superficial skin erosion wounds healing

Gao

Wang

Xia

et al. 2019

International Wound Journal

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Superficial skin erosion wounds are very common in the clinic, and conventional treatments are not always effective; thus, effective and novel therapy is needed. Cold atmospheric plasma (CAP) has been recognised as a promising approach to wound healing. The purpose of this study is to show the potential clinical application of CAP for the healing of different kinds of superficial skin wounds. Seven patients with different kinds of superficial skin wounds (two patients with pyoderma gangrenosum, two patients with trauma would, one patient with giant genital wart, one patient with diabetic foot, and one patient with chronic eczema) were recruited to this study. All patients accepted and received CAP treatment every other day till the wound healed. The expected results were complete wound healing after CAP treatment. All patients achieved complete wound healing after several rounds (range from two to eight) of CAP treatment, and there was no side effect observed. CAP may provide a new and effective choice to solve the problem of the healing of superficial wounds that are not only caused by trauma but also because of eczema. CAP has certain value in the treatment of superficial skin diseases in the future.

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Section: Discussionmentioning

confidence: 99%

Cold atmospheric plasma promotes different types of superficial skin erosion wounds healing

Gao

Wang

Xia

et al. 2019

International Wound Journal

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“…Previous studies showed recurrence rates of 3%-77%, 20%-79%, 8%-35% and 23%-70% when lesion treatment had done with holmium laser, cryotherapy, conventional surgery and podophyllin respectively. 7,11,16,20 The results of this study showed treatment with holmium laser is correlated with highest clearance rate (92.2%) and lowest recurrence rate (14.3%) than other applied treatments. In conclusion, holmium laser is safe, and more effective, than other methods in management of genital warts.…”

Section: Discussionmentioning

confidence: 57%

“…Mechanism of this advanced technology is photothermal destruction, that makes it possible to remove even the largest warts. 11 However, there are few studies about the use of holmium laser in the treatment of genital warts. This retrospective study compared the success rate of holmium laser with other genital wart treatments.…”

Section: Introductionmentioning

confidence: 99%

Is Holmium Laser an Appropriate Modality to Treat Genital Warts?

et al. 2018

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Introduction: Genital warts in young adults aged 18-28 years are very common. Several approaches are routinely used in the treatment of warts, viz., medical treatment (podophyllin and trichloroacetic acid), conventional surgery (excision or electrocautery), cryotherapy, and laser treatment. Because of high recurrence rates after treatment, complications and long duration of treatment, newer modalities have been developed. One of these newer methods is laser, which has been used in several urologic diseases. However, there are only a few studies about use of Holmium laser for treatment of genital warts. This retrospective study compared the success rate of Holmium laser with other available treatments for genital warts. Methods: Between October 2011 and May 2016, 142 patients with genital warts attended the urology clinics at Shohada-e-Tajrish hospital in Tehran, Iran. Out of these, a total of 101 patients were included in this study consisting of 42, 39, 11 and 9 patients treated with cryotherapy, laser, conventional surgery and podophyllin respectively. Results: The most successfully cleared lesions were seen in the holmium laser treatment group (P=0.001). The lowest recurrence rate was observed in the holmium laser treatment group (P=0.001). 17 patients had one of these following problems: dysuria, initial hematuria or a change in the force and caliber of their urinary stream that after physical examination showed them to have a meatal wart. These patients then underwent cystoscopy up to urinary sphincter. All of them in addition to the meatus wart had a penile shaft lesion(s). Thirteen patients had meatal lesions, 9 of whom received holmium laser therapy and 4 patients were treated with electrocautery. Based on routine follow up after treatment, none of the patients treated with holmium laser had urinary stricture, but one case treated with electrocautery returned with a penile urethral stricture. Conclusion: This study showed that treatment with Holmium laser has the highest clearance rate (92.2%) and lowest recurrence rate (14.3%) compared to other available treatments in this study. It may be concluded that holmium laser is a safe and effective treatment for genital warts with a low rate of recurrence.

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“…This laser has been used for treatment of genital warts in our clinic for 6 years, with a satisfactory curative effect, especially in the treatment of giant genital warts. 11 In conclusion, PG in laser-treated PWSs is a rare condition. Although there are several reports of adverse effects and complications of 595-nm PDL treatment, PG has not been documented as a side effect or complication.…”

Section: Discussionmentioning

confidence: 89%