Holographic Optical Tweezers: Techniques and Biomedical Applications

Chen, Hui‐Chi; Cheng, Chau Jern

doi:10.3390/app122010244

Cited by 21 publications

(10 citation statements)

References 146 publications

(222 reference statements)

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“…Computer generated holograms (CGH) are widely used in different scientific and technological fields, such as biomedical field 10,11 , 3D imaging 12 , image encryption 13 , etc. The generation of CGH involves the computation of the diffraction field of the light sources on the surface of the object.…”

Section: Introductionmentioning

confidence: 99%

Multiple-image authentication scheme based on the phase-only holograms

Jiang,

Sui,

Wang

et al. 2024

International Conference on Optical and Photonic Engineering (icOPEN 2023)

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Section: Introductionmentioning

confidence: 99%

Multiple-image authentication scheme based on the phase-only holograms

Jiang,

Sui,

Wang

et al. 2024

International Conference on Optical and Photonic Engineering (icOPEN 2023)

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“…In recognition of the breakthrough in trapping and manipulating microparticles, Arthur Ashkin [1] and his co-worker were awarded the Nobel Prize in Physics in 2018 for their pioneering work on OTs. In recent years, researchers have built upon Ashkins work by developing various types of OTs, which include holographic optical tweezers [2] , thermoelectric optical tweezers [3][4][5] , surface plasmon polarization optical tweezers [6,7] , near-field evanescent wave optical tweezers [8] , and fiber optical tweezers [9,10] . OTs have expanded the applications from cell trapping [11] to cell sorting [10,12] , Raman spectroscopy detection [5,13] , and other fields.…”

Section: Introductionmentioning

confidence: 99%

Force analysis of optical fiber tweezers with different endface configurations

Gao,

Ran,

Wang

et al. 2024

Advanced Fiber Laser Conference (AFL2023)

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The optical tweezers (OT) use optical force to trap micro/nano particles. This technology has widely been employed in manipulating cells, viruses and atoms, etc. Optical fiber tweezers (OFT), as a novel type of OTs, possess excellent characteristics of easy fabrication, strong anti-interference ability, high compatibility with chip devices, and flexible operation with a compact structure. Usually, the OFT probes are tapered, but they have a low optical trap strength, which makes it difficult to capture smaller particles (sub-micron size). In this study, we demonstrate theoretical analyses of the fields and optical forces with different fiber structures, including the tapered, spherical, hemispherical, zone plate, and gold-overlapped endface. Numerical simulations are carried out to investigate the magnitude and direction of the optical force exerted on microparticles in water. The results reveal that the shape of the fiber endface structure significantly alters the distribution of the optical field. The hemispherical and tapered endface have a similar ability to trap microparticles.The spherical and zone plate endface is better than the two endface mentioned above. Meanwhile, the use of goldoverlapped fiber tips can strongly constrain the dielectric microparticles on the endface, achieving effective twodimensional trapping. This research offers theoretical guidance for designing and optimizing fiber endface structures for efficient optical micro-manipulations.

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“…One of the most commonly used iterative algorithms for designing Fourier transform holograms is the Gerchberg–Saxton (GS) algorithm, which has the characteristics of simple programming, fast convergence, and strong versatility. In 2002, the GS algorithm was first introduced into the field of optical tweezers by Curtis et al [ 9 ], and since then, GS algorithm has been widely used in many improvements and optimizations [ 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 ], including a weighted Gerchberg–Saxton algorithm [ 18 , 19 , 20 ].…”

Section: Introductionmentioning

confidence: 99%

Holographic Optical Tweezers That Use an Improved Gerchberg–Saxton Algorithm

Zhou

Zhao

et al. 2023

Micromachines

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It is very important for holographic optical tweezers (OTs) to develop high-quality phase holograms through calculation by using some computer algorithms, and one of the most commonly used algorithms is the Gerchberg–Saxton (GS) algorithm. An improved GS algorithm is proposed in the paper to further enhance the capacities of holographic OTs, which can improve the calculation efficiencies compared with the traditional GS algorithm. The basic principle of the improved GS algorithm is first introduced, and then theoretical and experimental results are presented. A holographic OT is built by using a spatial light modulator (SLM), and the desired phase that is calculated by the improved GS algorithm is loaded onto the SLM to obtain expected optical traps. For the same sum of squares due to error SSE and fitting coefficient η, the iterative number from using the improved GS algorithm is smaller than that from using traditional GS algorithm, and the iteration speed is faster about 27%. Multi-particle trapping is first achieved, and dynamic multiple-particle rotation is further demonstrated, in which multiple changing hologram images are obtained continuously through the improved GS algorithm. The manipulation speed is faster than that from using the traditional GS algorithm. The iterative speed can be further improved if the computer capacities are further optimized.

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Holographic Optical Tweezers: Techniques and Biomedical Applications

Cited by 21 publications

References 146 publications

Multiple-image authentication scheme based on the phase-only holograms

Multiple-image authentication scheme based on the phase-only holograms

Force analysis of optical fiber tweezers with different endface configurations

Holographic Optical Tweezers That Use an Improved Gerchberg–Saxton Algorithm

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