Holstein İneklerde GH/AluI Polimorfizmi ile Bazı Süt Verim Özellikleri Arasındaki İlişkiler

Sönmez, Zeynep; Özdemir, Memiş; Bayram, Bahri; Aksakal, Vecihi

doi:10.24925/turjaf.v6i5.602-606.1838

Cited by 7 publications

(3 citation statements)

References 2 publications

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“…Pal et al [14] showed that crossbred males with the bGH-AluI LL genotype demonstrated higher expected milk productivity. It was shown in other studies on Holstein cows that the total milk yield in animals with the bGH-AluI LV and bGH-AluI VV genotypes was significantly higher than in cows with the bGH-AluI LL genotype, which suggests the dominance of the bGH-AluI V allele [15][16][17][18]. Our results also showed that black-and-white cows with the bGH-Alu-I LV genotype have higher milk yield.…”

Section: Discussionsupporting

confidence: 72%

Preferred and undesirable genotypes of bGH and bIGF-1 genes for the milk yield and quality of black-and-white breed

et al. 2021

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Background and Aim: The market demand for the quality of milk and dairy products, in particular in terms of such indicators as fat content, the amount and composition of milk protein, etc., is growing. Thus, the need for the selection of dairy herds using genetic markers associated with qualitative traits of milk productivity is becoming urgent. This study aimed to determine the preferred and undesirable genotypes of the AluI polymorphism of the growth hormone gene and SnaBI polymorphism of the insulin-like growth factor-1 gene associated with milk productivity and quality indicators of the black-and-white breed. The genotypes of animals were determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Materials and Methods: Samples of the black-and-white breed from Kazakhstan served as the research subjects. The polymorphism of the growth hormone and insulin-like growth factor-1 genes was determined by PCR-RFLP. The relationship of bGH-AluI and bIGF-1-SnaBI polymorphisms with productivity was assessed (fat, protein, and milk yield for 305 days of lactation, live weight, somatic cells, and milk production coefficient) by analysis of variance using Statistica 6.0 software. Results: The black-and-white cows with the bGH-AluILV genotype had significantly higher milk yield in 305 days (3174.5±157.2 kg) than those with the bGH-AluILL (2940.0±152.6 kg) and bGH-AluIVV genotypes (2964.0±36.0; p<0.05). The milk fat content of cows with genotypes bGH-AluILV and bGH-AluILL (121.8±6.5 and 120.6±10.2, respectively) was significantly higher than those with bGH-AluIVV genotype (109.8±10.8; p<0.05). The black-and-white cows with the bGH-AluILV genotype (96.7±5.3) had significantly more milk protein than those with the bGH-AluILL (90.3±5.6) and bGH-AluIVV (86.9±4.6) genotypes (p<0.05). There were no statistically significant differences in the indicators of milk productivity of cows with different genotypes of bIGF-1-SnaBI polymorphism. Conclusion: The results showed that the bGH-AluILV genotype was preferred for the black-and-white breed. The study demonstrated that genotype determined the relevant qualities, while the conditions of feeding, maintenance, and industrial technology provided the manifestation of this genotype. Thus, cows of the same (Wis Burke Ideal) line, having common ancestors in close (IV–V) ranks but living in different farming conditions, had large differences in milk productivity level. The variation was 2046 kg or 67.6% of milk per lactation.

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Section: Discussionsupporting

confidence: 72%

Preferred and undesirable genotypes of bGH and bIGF-1 genes for the milk yield and quality of black-and-white breed

et al. 2021

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“…In two different studies in which we correlated the yields of GH/AluI gene polymorphisms in 118 and 186 numbers of Holstein cattle breeds from different farms, no significant relationship was found between genotypes and milk yields. A similar relationship could not be found between GH-AluI and IGFI-Sna-BI gene polymorphisms and milk yield in Simmental cattle (Sönmez et al, 2018;Özdemir et al, 2018). Therefore, considering our three association studies, we examined previous studies to determine the potential for these gene regions to be used as markers.…”

Section: Discussionmentioning

confidence: 90%

Effects of Somatotropic Axis Gene Polymorphisms on Milk Yields in Simmental Cattle

Sonmez,

Kopuzlu,

Özdemir

2024

J Hellenic Vet Med Soc

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Due to the increasing world population, scientists aim to obtain high-yield products using new techniques and methods to meet needs in the fields of food, agriculture, and livestock. It is very important to selected the candidate genes and markers correctly, especially in the QTL and MAS techniques in livestock. Somatotropic axis genes affect yield traits, growth, reproduction, and milk production in cattle. In the study, we determined GH/AluI and IGFI/SnaBI gene polymorphisms using the PCR-RFLP technique in DNA samples obtained from 70 Simmental cattle. The allele frequencies of the genes were in the same proportion as 0.62 and 0.38, L and V for the GH gene and T and C for the IGFI gene. There was no significant relationship between the polymorphic genotypes of the genes we examined and lactation milk yields, 305-day milk yields, daily milk yields, and lactation periods of Simmental cattle. The probability of using bGH/AluI and IGFI/SnaBI genetic variations as markers in association studies with milk yield in cattle is extremely low. Keywords: Axis genes; RFLP; MAS; Simmental; milk yield

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“…The bovine GH gene is located on chromosome 19q and contains four introns and five exons. GH is considered a candidate gene associated with growth, milk and reproduction traits (Curi et al, 2006;Dario et al, 2005;Grochowska et al, 2001;Pereira et al, 2005;Sönmez et al, 2018). Researchers have identified several polymorphisms in the GH gene (Amiri et al, 2018;Bordonaro et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

A meta-analysis of the association between Growth Hormone (GH) gene polymorphism and growth traits in cattle breeds

Bayraktar

Özdemir²

2022

J Hellenic Vet Med Soc

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GH gene is one of the important genes that affect the productive and physiological traits in livestock. This study aimed to use a meta-analysis to determine the association of the GH gene with growth traits in cattle. Four different genetic models were used: dominant LL + LV versus VV, recessive LL versus LV + VV, complete over dominant LL+VV vs. LV and co-dominant LL vs. LV, LL vs. VV and LV vs. VV. The random-effect model was used in data analysis based on I2. Meta-analysis showed an effect of GH genotypes on the birth weight (BW) under the recessive (p<0.05) and complete over dominant (p<0.01) models. However, no association (p>0.05) was found under the dominant model. In terms of co-dominant model, the GH polymorphism showed a significant association with BW (SMD = 0.359, 95% CI = 0.119 to 0.599, p = 0.003) under LL vs. LV genotype combination patterns. No association was found between GH polymorphism and BW under LL vs. VV genotype combination. The results showed that the LL genotype had a significant effect on BW traits from LV and VV genotypes when comparing the models. The results showed an effect of the GH on ADG under four genetic models (p<0.05).

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Holstein İneklerde GH/AluI Polimorfizmi ile Bazı Süt Verim Özellikleri Arasındaki İlişkiler

Cited by 7 publications

References 2 publications

Preferred and undesirable genotypes of bGH and bIGF-1 genes for the milk yield and quality of black-and-white breed

Preferred and undesirable genotypes of bGH and bIGF-1 genes for the milk yield and quality of black-and-white breed

Effects of Somatotropic Axis Gene Polymorphisms on Milk Yields in Simmental Cattle

A meta-analysis of the association between Growth Hormone (GH) gene polymorphism and growth traits in cattle breeds

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