Home administration of bortezomib: Making a difference to myeloma patients' lives

Meenaghan, Teresa; O’Dwyer, Michael; Hayden, Patrick; Hayat, Amjad; Murray, Margaret; Dowling, Maura

doi:10.1016/j.ejon.2009.09.003

Cited by 7 publications

(5 citation statements)

References 7 publications

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“…This program was the first home IV chemotherapy program in the Republic of Ireland for children and adolescents with cancer. Currently, only one other published home IV chemotherapy program is available in Ireland, and this involves the administration of IV Bortezomib by nurses to adults in the home (Meenaghan et al, 2010). This service is not offered to children.…”

Section: Introductionmentioning

confidence: 99%

Administration of Home Intravenous Chemotherapy to Children by their Parents

McCall

Mannion

Hilliard

et al. 2016

J Pediatr Oncol Nurs

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Section: Introductionmentioning

confidence: 99%

Administration of Home Intravenous Chemotherapy to Children by their Parents

McCall

Mannion

Hilliard

et al. 2016

J Pediatr Oncol Nurs

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“…- Cancer (n = 22; 34.4%): Twelve (54.5%) home care services were designed for patients with solid tumors, 25-38 while the rest (n = 10; 45.5%) were aimed at patients with lymphoproliferative disorders (leukemia, multiple myeloma, and lymphoma). 39-48…”

Section: Resultsmentioning

confidence: 99%

“…It helps patients to better balance their lives with treatment by avoiding admission or traveling to the hospital. 21,25,26,28,30,32,40,43,47,54,78 Nurses led most of the home administration services with specific training in the different pathologies and extensive experience in the home administration of intravenous treatment. 21,31 Nurses were mainly responsible for administering the medication at home or teaching patients how to self-administer it, as well as monitoring symptoms and adverse events related to the medication.…”

Section: Discussionmentioning

confidence: 99%

Impact of Home Care Services on Patient and Economic Outcomes: A Targeted Review

Lizano-Díez

Amaral-Rohter

Pérez–Carbonell

et al. 2021

Home Health Care Management & Practice

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Patient Support Programs (PSPs) reinforce patients’ care provided by health care professionals with the aim to improve adherence and patient empowerment. PSPs may include interventions such as home-based care, individualized medication counseling, support, training, and home delivery of medicines and/or devices. This study described these services and its impact on patient-reported outcomes and health care savings. We conducted an integrative literature review which was limited to publications from the last 10 years (2009-2019) and focused on diseases that require special support and/or parenteral administration. From 7040 total citations, we identified 64 home-based care services performed worldwide. Among the home-based care services, most were provided by nurses (n = 47/64; 73.4%) and addressed to cancer patients (n = 22/64; 34.4%); 23 out of 64 services (35.9%) incorporated telepharmacy. In general, home-based services and PSPs showed a positive impact on patients’ adherence to medication, patient satisfaction, and health-related quality of life. In addition, 14 (21.9%) services reported economic results, most of which showed that home therapy led to substantial cost savings.

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“…In one case, bortezomib administration in myeloma patients was performed at home from the first dose without significant problems [15]. Given the current national guidelines established in 2003, we have favored the first day of each cycle of therapy with bortezomib at the outpatient care unit [16].…”

Section: Discussionmentioning

confidence: 99%

“…In one nursing study [15], from the patient and family point of view, the advantages of chemotherapy injection at home are numerous: being in one’s own environment leading to less disturbances to daily life, less time in transit and less fatigue, and the ability to continue a professional activity. All these aspects of treatment management at home have been shown to improve or maintain quality of life [19–22].…”

Section: Discussionmentioning

confidence: 99%

Cost savings of home bortezomib injection in patients with multiple myeloma treated by a combination care in Outpatient Hospital and Hospital care at Home

Touati

Lamarsalle²,

Moreau

et al. 2016

Support Care Cancer

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At home injectable chemotherapy for patients receiving treatment for hematological diseases is still in debate. Given the expense of new innovative medicines, at home treatment has been proposed as a suitable option for improving patient quality of life and decreasing treatment costs. We decided to assess the cost of bortezomib administration in France among multiple myeloma patients from an economic standpoint. Patients in this study were treated within a regional hematological network combining outpatient hospital care and Hospital care at Home administration. To make the cost comparison, our team simulated outpatient hospital care expenses. Fifty-four consecutive multiple myeloma patients who received at least one injection of bortezomib in Hospital care at Home from January 2009 to December 2011 were included in the study. The median number of injections was 12 (range 1–44) at home and 6 (range 0–30) in the outpatient care unit. When compared with the cost simulation of outpatient hospital care alone, bortezomib administration with combined care was significantly less expensive for the National Health Insurance (NHI) budget. The mean total cost per patient and per injection was 954.20 € for combined outpatient and Hospital care at Home vs 1143.42 € for outpatient hospital care alone. This resulted in an estimated 16.5 % cost saving (Wilcoxon signed-rank test, p < 0.0001). The greatest savings were observed in administration costs (37.5 % less) and transportation costs (68.1 % less). This study reflects results for a regionally implemented program for multiple myeloma patients treated with bortezomib in routine practice in a large rural area.Electronic supplementary materialThe online version of this article (doi:10.1007/s00520-016-3363-3) contains supplementary material, which is available to authorized users.

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Home administration of bortezomib: Making a difference to myeloma patients' lives

Cited by 7 publications

References 7 publications

Administration of Home Intravenous Chemotherapy to Children by their Parents

Administration of Home Intravenous Chemotherapy to Children by their Parents

Impact of Home Care Services on Patient and Economic Outcomes: A Targeted Review

Cost savings of home bortezomib injection in patients with multiple myeloma treated by a combination care in Outpatient Hospital and Hospital care at Home

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