2013
DOI: 10.1016/j.apmr.2012.08.215
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Home-Based Overnight Transcutaneous Capnography/Pulse Oximetry for Diagnosing Nocturnal Hypoventilation Associated With Neuromuscular Disorders

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Cited by 37 publications
(29 citation statements)
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“…Screening with early and periodic nocturnal oximetry and when feasible following up abnormal nocturnal oximetry with polysomnography may improve detection of central control dysfunction. Alternatively, advancements in technology resulting in more reliable transcutaneous capnography, even accommodating home based overnight monitoring, present an attractive consideration …”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Screening with early and periodic nocturnal oximetry and when feasible following up abnormal nocturnal oximetry with polysomnography may improve detection of central control dysfunction. Alternatively, advancements in technology resulting in more reliable transcutaneous capnography, even accommodating home based overnight monitoring, present an attractive consideration …”
Section: Resultsmentioning
confidence: 99%
“…Alternatively, advancements in technology resulting in more reliable transcutaneous capnography, even accommodating home based overnight monitoring, present an attractive consideration. 39,40 Still to be determined is the significance of the benefit, if any, in detecting and treating dysfunction of central control of breathing in ALS patients. Opportunities include defining the impact on cognition, quality of life, disease progression, and survival.…”
Section: Resultsmentioning
confidence: 99%
“…These criteria may be difficult to find in the absence of daytime hypercapnia. However, using a more liberal definition, nocturnal hypoventilation with an arterial Pa CO 2 greater than or equal to 50 mm Hg for greater than or equal to 5% of monitoring in adults or greater than or equal to 2% of monitoring time in children is seen in more than 40% of subjects with neuromuscular disease not using noninvasive ventilation and with no daytime hypercapnia (37,38). An average increase in Pa CO 2 of 20 mm Hg during sleep may be seen in neuromuscular diseases (39).…”
Section: Nocturnal Hypoventilationmentioning
confidence: 99%
“…Although the goal of noninvasive ventilation is not necessarily to normalize the nocturnal Pa CO 2 (86), 53% of neuromuscular subjects on nocturnal ventilation still have nocturnal hypoventilation (37). Guidelines to address obstructive sleep-disordered breathing, hypoventilation events, and asynchrony on polysomnography have been published (97).…”
Section: Positive Airway Pressure Titrationmentioning
confidence: 99%
“…Lesions impacting voluntary breathing are most commonly secondary to ischemic stroke, but may also be secondary to pontine tumor, pontine myelinolysis, high cervical demyelination, syphilitic arteritis of the medulla, diffuse cortical vascular disease, and head injury [21,22]. Extrapyramidal disorders such as Parkinsonism have also been associated with impaired voluntary control of breathing as well as SRBDs [23].…”
Section: Diseases Of the Central Nervous Systemmentioning
confidence: 99%