Home-based, supervised, and mixed exercise intervention on functional capacity and quality of life of colorectal cancer patients: a meta-analysis

Kang

et al. 2022

Cancers

Background: Uncertainty exists regarding the associations between physical activity (PA), relative handgrip strength (RHGS), and health-related quality of life (HRQoL) among elderly Korean cancer survivors. This study investigated the moderating effect of RHGS on the relationship between PA and HRQoL in 308 cancer survivors aged ≥65 years using the data from the Korean National Health and Nutrition Examination Survey in 2014–2019. Methods: HRQoL was evaluated with the EuroQol-5-dimension instrument. PA and handgrip strength were assessed with the Global Physical Activity Questionnaire and a hand dynamometer, respectively. Age, sex, body mass index, income, marital status, educational background, heavy alcohol consumption, smoking status, multimorbidity, and hemoglobin were included as covariates. Results: Bivariate logistic regression showed that insufficient PA and no PA were associated with higher odds of a low HRQoL (odds ratio, OR = 2.6, 95% confidence interval, CI = 1.3~5.1, p = 0.005; OR = 2.4, 95% CI = 1.1~5.0, p = 0.024, respectively), compared with sufficient PA (OR = 1). Weak RHGS was associated with high odds of a low HRQoL (OR = 2.6, 95%= 1.530~4.6, p < 0.001) compared with normal RHGS (OR = 1). Particularly, RHGS (β = −0.0573, 95% CI = −0.1033~−0.0112) had a significant moderating effect on the relationship between PA and HRQoL even after adjustments for all the covariates. The negative influence of physical inactivity on HRQoL was observed in cancer survivors with weak RHGS but not in cancer survivors with normal RHGS. Conclusions: The current findings suggest that maintaining or promoting muscular strength through regular exercise is critical for the HRQoL of elderly Korean cancer survivors.

Section: Discussionmentioning

confidence: 99%

Associations of Physical Activity and Handgrip Strength with Health-Related Quality of Life in Older Korean Cancer Survivors

Kang

et al. 2022

Cancers

“…Epidemiological studies in childhood cancer survivors support that exercise lowers long-term risk of serious cardiac events, and there is a randomized control trial (RCT) developed specifically to investigate the impact of exercise on cardiovascular risk factors with results pending (5). Small studies have shown positive effects in the adult population of at-home exercise interventions and RCTs have shown promising outcomes of exercise effect on cancer-related fatigue and quality of life (34,35). Nonetheless, cardiac-related outcomes need to be better studied in the pediatric population (5).…”

Section: Cardiotoxicitymentioning

confidence: 99%

Clinical Considerations in Returning Pediatric and Young Adults With Cancer to Physical Activity

Dykowski,

Simoneau,

Smith

et al. 2023

Curr Sports Med Rep

There is a gap in the literature on the best treatment of clinical sequelae within adolescent and young adult pediatric cancer populations. Children, adolescents, and young adults are at risk for a multitude of immediate and late effects of their disease and treatment that warrant a comprehensive, multidisciplinary team approach to optimize care. Sports medicine providers are well-equipped with their background to join the oncology rehabilitation team in diagnosing and managing cancer-related impairments to help these populations live a healthier and more active lifestyle. In this manuscript, four essential clinical components to consider when returning children, adolescents, and young adults with cancer history to physical activity are discussed: chemotherapy-induced peripheral neuropathy, cardiotoxicity, nutritional deficiencies, and deconditioning.

“…Home-based exercise programs can be a feasible strategy to improve breast cancer survivors' PA levels, quality of life, and functional performance, overcoming commonly reported barriers to PA practice, such as the lack of time, motivation, travelling, and nancial issues [13], [14]. A systematic review investigating the health outcomes of nine home-based exercise interventions in cancer survivors showed high adherence levels (71-88%) in ve of them and multiple physiological bene ts [15].…”

Section: Introductionmentioning

confidence: 99%

A supervised home-based exercise program for breast cancer survivors' functional performance (Home-PAC): a pilot study

Ramos

Júdice

Valadas

et al. 2023

Preprint

Introduction. Hormonal therapy has adverse effects that hinder breast cancer survivors' functional performance and quality of life. Physical activity (PA) can counteract these adverse effects, and home-based exercise interventions might be a potential solution to foster PA adoption in this population. This study aimed to investigate home-based exercise intervention effects on functional performance, quality of life and PA of breast cancer survivors’ undergoing hormonal therapy. Adherence to the intervention and adverse events were also reported. Method. This study was a 12-week randomised controlled trial comprising a home-based exercise intervention supported by an exercise booklet including six exercise groups and a weekly online exercise group session. Eighteen women were recruited from Hospital Universitário do Barlavento Algarvio. Results. Significant time-by-group effects in functional performance (sit-to-stand (p=.033), arm curl (p=.011), and timed up-and-go (.009) tests), quality of life (insomnia (p=.007) and breast symptoms (p=.035)), and PA (vigorous PA (p=.033), walking (p=.005), and total PA (p=.034)), favouring the intervention group were found. Attendance to the supervised component of the program was high (80%). Conclusion. This home-based exercise intervention was well tolerated and accepted by participants and led to significant improvements in functional performance and PA levels. These findings further support the effectiveness of this type of intervention, which is a more affordable and viable strategy to raise PA levels and enhance functional performance in breast cancer survivors. Exercise professionals may use these programs to promote active lifestyles while reducing barriers to practice.