Home Oxygen Therapy

Sauvé, Reg; McMillan, DD; Mitchell, Ian; Creighton, Dianne; Hindle, N. Warren; Young, Loretta

doi:10.1177/000992288902800301

Cited by 31 publications

(2 citation statements)

References 25 publications

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“…However, there is a lack of general consensus regarding home oxygen use in VLBWIs among neonatal intensive care units (NICUs). Moreover, because infants receiving home oxygen are usually expected to have frequent healthcare utilization related to their original morbidities, appropriate follow-up plans after NICU discharge must be established, with basic knowledge regarding their follow-up courses (89). However, to date, there are no actual data regarding home oxygen use in VLBWIs discharged from the NICU in Korea.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Follow-up Courses after Discharge from Neonatal Intensive Care Unit between Very Low Birth Weight Infants with and without Home Oxygen

et al. 2017

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In order to investigate the clinical impact of home oxygen use for care of premature infants, we compared the follow-up courses after neonatal intensive care unit (NICU) discharge between very low birth weight infants (VLBWIs) with and without home oxygen. We retrospectively identified 1,232 VLBWIs born at 22 to 32 weeks of gestation, discharged from the NICU of 43 hospitals in Korea between April 2009 and March 2010, and followed them up until April 2011. Clinical outcomes, medical service uses, and readmission and death rates during follow-up after the NICU discharge were compared between VLBWIs with (HO, n = 167) and those without (CON, n = 1,056) home oxygen at discharge. The HO infants comprised 13.7% of the total VLBWIs with significant institutional variations and showed a lower gestational age (GA) and birth weight than the CON infants. The HO infants had more frequent regular pediatric outpatient clinic visits (12.7 ± 7.5 vs. 9.5 ± 6.6; P < 0.010) and emergency center visits related to respiratory problems (2.5 ± 2.2 vs. 1.8 ± 1.4; P < 0.010) than the CON infants. The HO infants also had significantly increased readmission (adjusted hazard ratio [HR], 1.60; 95% confidence interval [CI], 1.25–2.04) and death risks (adjusted HR, 7.40; 95% CI, 2.06–26.50) during up to 2 years following the NICU discharge. These increased readmission and death risks in the HO infants were not related to their prematurity degree. In conclusion, home oxygen use after discharge increases the risks for healthcare utilization, readmission, and death after NICU discharge in VLBWIs, regardless of GA, requiring more careful health care monitoring during their follow-up.

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Section: Introductionmentioning

confidence: 99%

Comparison of Follow-up Courses after Discharge from Neonatal Intensive Care Unit between Very Low Birth Weight Infants with and without Home Oxygen

et al. 2017

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“…Yet, contrary to our hypothesis, these infants with BPD with chronic oxygen dependency did not have a higher incidence of neurodevelopmental disability at 3 years CA. While earlier studies had predicted worse neurodevelopmental outcomes of infants with BPD sent home on supplemental oxygen [52], recent reports are more in line with our results [53], [54]. In one study, there was a difference in developmental scores at the 1 and 2 years follow up, but at 4 years CA, there were no differences in the BPD-room air and BPD-home oxygen groups, suggesting a catch-up between 2 and 4 years CA [53].…”

Section: Discussionmentioning

confidence: 90%

Need for Supplemental Oxygen at Discharge in Infants with Bronchopulmonary Dysplasia Is Not Associated with Worse Neurodevelopmental Outcomes at 3 Years Corrected Age

et al. 2014

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ObjectivesTo determine if chronic oxygen dependency (discharge home on supplemental oxygen) in children with bronchopulmonary dysplasia (BPD; defined as requirement for supplemental O2 at 36 weeks postmenstrual age) predicts neurodevelopmental disability rates and growth outcomes at 36 months corrected age (CA).Study DesignLongitudinal cohort study.SettingSouthern Alberta regional center located at high altitude.ParticipantsPreterm infants weighing ≤1250 grams with no BPD, BPD, and BPD with chronic oxygen dependency.Main outcome measuresNeurodevelopmental and growth outcomes.ResultsOf 1563 preterm infants admitted from 1995–2007, 1212 survived. Complete follow-up data were available for 1030 (85%) children. Children in BPD and BPD with chronic oxygen dependency groups had significantly lower birth weights, gestational ages, prolonged mechanical ventilation and oxygen supplementation and received more postnatal steroids, compared to those without BPD. Children with BPD and BPD with chronic oxygen dependency were more likely to be below the 5th centile in weight and height compared to those without BPD but there was little difference between the BPD and BPD with chronic oxygen dependency groups. After controlling for confounding variables, children who had BPD and BPD with chronic oxygen dependency had higher odds of neurodevelopmental disability compared to those without BPD [OR (odds ratio) 1.9 (95%CI 1.1 to 3.5) and OR 1.8 (1.1 to 2.9), respectively], with no significant difference between BPD and BPD with chronic oxygen dependency [OR 0.9 (95% CI 0.6 to 1.5)].ConclusionsBPD and BPD with chronic oxygen dependency in children predicts abnormal neurodevelopmental outcomes at 36 months CA. However, the neurodevelopmental disability rates were not significantly higher in BPD with chronic oxygen dependency children compared to children with BPD only. Compared to those without BPD, growth is impaired in children with BPD and BPD with chronic oxygen dependency, but no difference between the latter two groups.

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Predictors of home oxygen duration in chronic neonatal lung disease

Wong

Neylan

Williams

et al. 2021

Pediatric Pulmonology

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Aims In infants with chronic neonatal lung disease (CNLD), we aimed to identify predictors of home oxygen duration, predictors of discharge oxygen flow rates, and the association of oxygen flow rates with respiratory outcomes. Methods Infants with CNLD requiring home oxygen in 2016 and 2017 were retrospectively reviewed. Hazard ratios (HR) were estimated from Cox proportional hazards regression models in the cohort. A multinomial logistic regression model examined the effects of maternal and infant variables on discharge oxygen flow rates. Kruskal–Wallis test with univariate linear regression and Fisher's exact test with binomial univariate logistic regression were used to examine associations between oxygen flow groups and post‐discharge clinical variables. Results One hundred and forty‐nine infants were included. Median corrected gestational age (CGA) at oxygen cessation was 6.8 months (interquartile range, 4.4) with 87.2% of infants weaned by 12 months CGA. Shorter initial neonatal intensive care unit (NICU) stay predicted faster oxygen weaning at 9 months (HR, 0.99; 95% confidence interval [CI], 0.98–1.00, p = .02) and 12 months (HR, 0.99; 95% CI, 0.98–1.00, p = .02). Infants with hypercarbia at discharge or discharged from NICU at higher CGA had higher odds of requiring ≥ 200 ml/min relative to ≤ 125 ml/min oxygen. Infants discharged with > 250 ml/min oxygen were more likely to have a respiratory‐related admission before 2 years chronological age. Conclusion Shorter initial NICU stay was the best predictor of earlier home oxygen cessation. At NICU discharge, infants with hypercarbia or a higher CGA may require more home oxygen and experience more respiratory‐related hospital admission in the first 2 years of chronological age.

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Home Oxygen Therapy

Cited by 31 publications

References 25 publications

Comparison of Follow-up Courses after Discharge from Neonatal Intensive Care Unit between Very Low Birth Weight Infants with and without Home Oxygen

Comparison of Follow-up Courses after Discharge from Neonatal Intensive Care Unit between Very Low Birth Weight Infants with and without Home Oxygen

Need for Supplemental Oxygen at Discharge in Infants with Bronchopulmonary Dysplasia Is Not Associated with Worse Neurodevelopmental Outcomes at 3 Years Corrected Age

Predictors of home oxygen duration in chronic neonatal lung disease

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