Homeostasis Changes of Tear-Producing System with the Background of Cosmetic Procedures in Periorbital Area

Трубилин, В. Н.; Полунина, Е. Г.; Анджелова, Д. В.; Куренков, В. В.; Капкова, С. Г.; Чиненова, К. В.

doi:10.18008/1816-5095-2018-4-424-432

Cited by 4 publications

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References 22 publications

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“…В литературе также описываются случаи, в которых инъекция ботулотоксина приводила к снижению объема слезопродукции. Обладая нейротропным действием, он может приводить к нарушению иннервации, в том числе и слезных желез [31].…”

Section: осложнения и побочные эффекты при лечении косоглазия методомunclassified

Prospects for the Botulinum Toxin Use in the Treatment of Children`s Strabismus. Review

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The review presents information concerning the botulinum toxin use in the treatment of children`s strabismus; highlights aspects of the safety and the complications frequency. It contains information about the methods and doses of botulinum toxin injection, and also considers the cases of necessity of further surgery. There are several ways of introducing BTA: the traditional transconjunctival method of administration under the control of electromyography, used by most ophthalmologists, is not acceptable for treating pediatric patients, transconjunctivally into the subtenon space 10 mm from the limbus into the projection zone of the medial rectus muscle using a 1.0 ml tuberculin syringe with 27G needle, introduction to the muscle with the opening of the conjunctiva, which is safer, is carried out under complete visual control and with the release of extraocular muscle. According to the domestic and foreign literature data we can conclude that the injection of botulinum toxin may be an alternative or complement to surgical techniques, injection of botulinum toxin in the treatment of strabismus in children may be an alternative or complement to surgical and pleopto-orthopto-diploptic correction methods, although not in all clinical cases. The treatment approach of such patients should be comprehensive. There are reports that BoNT-A reduces eye deflection in more than 50 % of patients and provides satisfactory long-term results in infants and children. The average safe dose for Botox is 1-3 units for the muscle. The frequency of complications increases with higher doses (especially> 10 units) and with the transconjunctival route of administration without electromyographic control. This clinical example illustrates the effectiveness of botulinum toxin for the non-concomitant strabismus treatment.

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Section: осложнения и побочные эффекты при лечении косоглазия методомunclassified

Prospects for the Botulinum Toxin Use in the Treatment of Children`s Strabismus. Review

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“…Отдельное место в современном офтальмологическом мире занимают факторы риска развития ССГ, связанные с косметологическими воздействиями в периорбитальной зоне. Опыт наблюдения за пациентами, данные литературы, а также проведенное нами исследование показали, что различного рода косметологические воздействия в периорбитальной зоне, популярность которых в последние годы возрастает, могут обусловить появление ятрогенного синдрома сухого глаза [52,53]. Проведение косметологических процедур в периорбитальной области (татуаж век, инъекции ботулотоксина, дермальных филлеров, наращивание ресниц) негативным образом отражается на состоянии глазной поверхности и слезопродуцирующей системы.…”

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Current Concepts about the Etiology of Dry Eye Syndrome

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The revolution in understanding the etiology and clinical manifestations of the disruption of the tearing process and the development of dry eye syndrome (CVS) has occurred in last 20–30 years. It has been established that the loss of the tear film homeostasis can occur not only because of a violation of systemic and autoimmune disorders, but also as a result of a blinking disorder and distribution of the tear film over the ocular surface. Therefore, new pathogenetic disease development mechanisms have been identified. The prevalence of diseases of the ocular surface and CVD in recent years has increased significantly. It is mostly caused not only by scientific discoveries in the field of understanding, for example, the etiological and pathophysiological role of the neurosensory mechanism of development of CVS. An important aspect is the emergence of new risk factors that potentiate the development of ocular surface diseases and CVL. These factors include the use of various drugs — antidepressants, antihistamines, hormone therapy, and others; instillation of eye drops — antiglaucoma drugs, etc., as well as the appearance of little-studied factors such as cosmetology procedures (eyelids tattooing, eyelash extensions, botulinum toxin injections for aesthetic purposes, etc.). They are carried out in proximate close to the eye and eyelids, causing multiple pathological reaction. The experience of observing patients, literature data, and the conducted study have showed that various cosmetological effects in the periorbital zone, whose popularity has increased in recent years, may cause the appearance of iatrogenic dry eye syndrome. The following most vivid clinical examples will help, encountered in our practice, to illustrate the data presented. Collecting the anamnesis, it is necessary to identify the presence of risk factors for the development of diseases of the ocular surface and CVD, to eliminate them, if possible, and to carry out adequate pathogenically based therapy.

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Diseases of the Ocular Surface Associated with Eyelid Makeup and Eyelash Extensions. Clinical Examples

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The environmental factors influence, quite often, negatively affects the state of health. Many of them, such as smoking, deterioration in ecology, uncontrolled alcohol intake, are in detail studied in terms of harm to a human body. Nevertheless, new technologies which action is insufficiently studied, are actively introduced into modern life. So, the use of cosmetology procedures can be a striking example. Now the prevalence of such procedures as eyelash extension, a permanent make-up a century, botulotoxin injections in a periorbital zone, assumes a wide scale. In foreign and domestic literature there are more and more messages about development of the complications which arose owing to use of the above-stated procedures. There are two clinical examples from our practice in this article. They demonstrate the complications which arose after holding a procedure of eyelash extension — acute toxic-allergic conjunctivitis and after a permanent make-up — a chemical burn of a cornea. In these clinical cases of a complication arose due to aggressive action of a chemical basis of the glue applied at eyelash extension and cream-anesthetic which is applied on eyelids before a permanent make-up a century. Treatment of patients included antiinflammatory, antihistaminic, antibacterial therapy and also a long course of the tear replacement therapy applied as keratoproteсtive therapy and for prevention of development of a dry eye syndrome. Considering scales of prevalence of cosmetology procedures in recent years, it is necessary to inform specialists and patients on potential risk of development of the complications connected with the above-stated procedures. The clinical examples given in the article and literature data, demonstrate that in case of cosmetology procedures complications it is necessary to carry out timely rendering the qualified medical ophthalmologic care. It is connected with the fact that, quite often, the cosmetology manipulations, even positioned as harmless, in particular, a permanent make-up of eyelid and eyelash extension can lead to heavy complications, up to vision loss.

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Homeostasis Changes of Tear-Producing System with the Background of Cosmetic Procedures in Periorbital Area

Cited by 4 publications

References 22 publications

Prospects for the Botulinum Toxin Use in the Treatment of Children`s Strabismus. Review

Prospects for the Botulinum Toxin Use in the Treatment of Children`s Strabismus. Review

Current Concepts about the Etiology of Dry Eye Syndrome

Diseases of the Ocular Surface Associated with Eyelid Makeup and Eyelash Extensions. Clinical Examples

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