We present a fully fiber-coupled source of high-fidelity single photons. An (In,Ga)As semiconductor quantum dot is embedded in an optical Fabry-Perot microcavity with a robust design and rigidly attached single-mode fibers, which enables through-fiber cross-polarized resonant laser excitation and photon extraction. Even without spectral filtering, we observe that the incident coherent light pulses are transformed into a stream of single photons with high purity (97%) and indistinguishability (90%), which is measured at an in-fiber brightness of 5% with an excellent cavity-mode-to-fiber coupling efficiency of 85%. Our results pave the way for fully fiber-integrated photonic quantum networks. Furthermore, our method is equally applicable to fiber-coupled solid-state cavity-QED-based photonic quantum gates. DOI: 10.1103/PhysRevApplied.9.031002 Every isolated two-level quantum system-for example, an atom, an ion, a color center, or a quantum dot-can, in principle, be turned into a bright single-photon source [1,2]. Ideally, such a source produces a stream of single photons, with never more or less than one photon per time bin, and with all having the same Fourier limited spectrum and timing. Such a source would be essential for the exploration of numerous quantum technologies, among them optical quantum computing [3-6] and simulation [7]. Furthermore, the reduced fluctuations of such single-photon light would enable exciting opportunities if noise is a limiting factor, in fields ranging from metrology to microscopy.However, only very recently have high-fidelity singlephoton sources been demonstrated [8][9][10][11][12][13] that simultaneously fulfill the key requirements: near-unity single-photon purity and indistinguishability of consecutively emitted photons, and high brightness. For a single-photon source, high brightness and on-demand availability is crucial for the efficient implementation of quantum photonic protocols. Additionally, to exploit the power of quantum interference, consecutively produced photons need to be indistinguishable, meaning that their wave functions must overlap well. Until recently, heralded spontaneous parametric down-conversion sources [14] were the state of the art for single-photon sources [15], with which most quantum communication and optical quantum computing protocols have been demonstrated [16]. The main problem with these sources is that the Poissonian statistics of the generated twin photons will always result in a trade-off between single-photon purity (the absence of N > 1 photon number states) and brightness (the probability of obtaining a photon per time slot).One way to deterministically produce single photons is to use trapped atoms [17], where single-photon rates up to around 100 kHz have recently been obtained [18]. In order to enable integration and an increase of the photon rate, solid-state systems have been investigated: of particular promise are semiconductor quantum dots (QDs) [1,19,20]. QDs have nanosecond-lifetime transitions that enable gigahertz-rate produc...