Homogeneous Time-Resolved Fluorescence DNA Hybridization Assay by DNA-Mediated Formation of an EDTA–Eu(III)–β-Diketonate Ternary Complex

Template-directed formation of luminescent lanthanide complexes: Versatile tools for colorimetric identification of single nucleotide polymorphism

“…However, Mut27C does not serve as an effective template for forming luminous complexes. The contrast in the emission intensities observed for the solution with and without targets were extremely high compared with previous studies of split-probing [56,57]. These results show the importance of being conscious of cooperativity when designing the system.…”

New cross-linking quinoline and quinolone based luminescent lanthanide probes for sensitive labeling

“…The testing experiments revealed high sensitivity of detection (less than 1 pM), unachievable with conventional fluorescencebased molecular beacons. The detection sensitivity was 10-60 times better than previously reported for the other lanthanide-based hybridization probes (23,24). Using covalent attachment of biotin residues to the cell, followed by incubation with avidin carrying multiple lanthanide chelates, resulted in highly intense cell labeling allowing detection of single cells.…”

Switchable lanthanide luminescent binary probes in efficient single nucleotide mismatch discrimination

“…Luminescent complex has previously been reported to form from adjacent hybridization of binary probes on a target nucleic acid in solution [32][33][34]. Self-assembly of a luminescent lanthanide complex has also been presented resulting from the enforced close proximity of a sensitizer and europium(III) complex immobilized on a glass [35] and gold [36] surfaces.…”