Readiness of new materials that are simultaneously lightweight, damage-resistant, multifunctional, and sustainable is a primary need for many technology sectors. Thanks to additive manufacturing, lattice materials appear to be ideal candidates to meet this challenge. By designing their unit cells and structural organization, multiscale materials with unique combinations of properties can be obtained. Nevertheless, many gaps remain to be filled for their effective and efficient design. Nature, exploiting hierarchical architectures on a material scale, actually amplifies the properties of biological materials and combines them in ways we cannot achieve yet in synthetic materials. In materials design, we are still far from such a level of perfection. To narrow this gap and expand the current knowledge on the effects of hierarchy on the mechanical behaviour of materials, we numerically studied the mechanical response of 3D hierarchical lattice specimens under a four-point bending loading scenario. For this, we selected two types of unit cells with different structural behaviour and combined them together into different specimen topologies. The results show that, through hierarchy, it is possible to tailor lattice material performances, achieving benefits in terms of both specific mechanical properties and multifunctionality. The evidence found opens new horizons for applications such as heat exchangers, mechanical filters, scaffolds, energy storage, and packaging.