Homograft insertion for pulmonary regurgitation after repair of tetralogy of Fallot improves cardiorespiratory exercise performance

Eyskens, Bénédicte; Reybrouck, Tony; Bogaert, Jan; Dymarkowsky, Steven; Daenen, Wim; Dumoulin, M; Gewillig, Marc

doi:10.1016/s0002-9149(99)00640-2

Cited by 145 publications

(75 citation statements)

References 27 publications

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“…[16][17][18][19] In that patient population, the impact of surgical pulmonary valve replacement on exercise function has been small. 7,20,21 It is possible that these disappointing outcomes are due, in part, to the trauma and debilitation inevitably associated with major open heart surgery.…”

Section: Discussionmentioning

confidence: 99%

Cardiopulmonary exercise function among patients undergoing transcatheter pulmonary valve implantation in the US Melody valve investigational trial

Batra

McElhinney

Wang

et al. 2012

American Heart Journal

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Section: Discussionmentioning

confidence: 99%

Cardiopulmonary exercise function among patients undergoing transcatheter pulmonary valve implantation in the US Melody valve investigational trial

Batra

McElhinney

Wang

et al. 2012

American Heart Journal

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“…The potential of detecting dilatation of the RV accurately on serial scanning can be of considerable use in the timing of surgery in patients with postoperative congenital heart disease (18). A prime example is in the serial follow-up of patients after corrective surgery for tetralogy of Fallot (19). This is important, as there is an increasing number of survivors of congenital heart disease surgery who eventually require further corrective surgery.…”

Section: Discussionmentioning

confidence: 99%

Comparison of right ventricular volume measurement between segmented k‐space gradient‐echo and steady‐state free precession magnetic resonance imaging

Alfakih

Thiele

Plein

et al. 2002

Magnetic Resonance Imaging

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Purpose:To compare right ventricular volume measurements and their reproducibility between steady-state free precession (SSFP) and conventional turbo gradient-echo (TGE) imaging. Materials and Methods:Right ventricular volumes and observer variabilities were compared between SSFP and TGE in 31 subjects (21 normal volunteers and 10 subjects with heart failure). For further internal validation of the right ventricular volumes, the left ventricle (LV) and right ventricle (RV) stroke volumes were compared for the normal volunteers. Results:The volumes as measured by SSFP were significantly larger than for TGE (mean bias end-diastolic volume [EDV] 11.1 Ϯ 14.2, end-systolic volume [ESV] 9.8 Ϯ 9.75). SSFP had lower interobserver variability (SSFP EDV -10.1 Ϯ 11.6 vs. TGE EDV -6.2 Ϯ 18.5) and intra-observer variability (SSFP EDV -2.0 Ϯ 6.3 vs. TGE EDV -6.1 Ϯ 14.8). The mean absolute differences between LV and RV stroke volumes for 21 normal volunteers were: TGE 5.8 Ϯ 12.9 (r 2 ϭ 0.72), SSFP 4.6 Ϯ 6.9 (r 2 ϭ 0.92).Conclusion: SSFP and TGE yield different measurement values of RV volumes with SSFP, providing a more reproducible measurement.

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“…2,5,6 Besides these beneficial effects of PVR on RV size and effective SV, we confirm an overall improvement in functional New York Heart Association class. 10 RV function did not change after surgery, but it remains unknown whether RV function stabilizes after surgery or declines steadily over time, as is the case before PVR. After the report by Vliegen et al, 2 an important issue was the question of whether the reported decrease in RV dilatation after surgery was only the result of the surgical reduction of the RV.…”

Section: Circulation July 31 2007mentioning

confidence: 94%

Preoperative Thresholds for Pulmonary Valve Replacement in Patients With Corrected Tetralogy of Fallot Using Cardiovascular Magnetic Resonance

et al. 2007

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Background-To facilitate the optimal timing of pulmonary valve replacement, we analyzed preoperative thresholds of right ventricular (RV) volumes above which no decrease or normalization of RV size takes place after surgery. Methods and Results-Between 1993 and 2006, 71 adult patients with corrected tetralogy of Fallot underwent pulmonary valve replacement in a nationwide, prospective follow-up study. Patients were evaluated with cardiovascular magnetic resonance both preoperatively and postoperatively. Changes in RV volumes were expressed as relative change from baseline. RV volumes decreased with a mean of 28%. RV ejection fraction did not change significantly after surgery (from 42Ϯ10% to 43Ϯ10%; Pϭ0.34). Concomitant RV outflow tract reduction resulted in a 25% larger decrease of RV volumes. After correction for surgical RV outflow tract reduction, higher preoperative RV volumes (mL/m 2 ) were independently associated with a larger decrease of RV volumes (RV end-diastolic volume: ␤ϭ0.41; PϽ0.001). Receiver operating characteristic analysis revealed a cutoff value of 160 mL/m 2 for normalization of RV end-diastolic volume or 82 mL/m 2 for RV end-systolic volume. Conclusions-Overall, we could not find a threshold above which RV volumes did not decrease after surgery. Preoperative RV volumes were independently associated with RV remodeling and also when corrected for a surgical reduction of the RV outflow tract. However, normalization could be achieved when preoperative RV end-diastolic volume was Ͻ160 mL/m 2 or RV end-systolic volume was Ͻ82 mL/m 2 . (Circulation. 2007;116:545-551.)

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Homograft insertion for pulmonary regurgitation after repair of tetralogy of Fallot improves cardiorespiratory exercise performance

Cited by 145 publications

References 27 publications

Cardiopulmonary exercise function among patients undergoing transcatheter pulmonary valve implantation in the US Melody valve investigational trial

Cardiopulmonary exercise function among patients undergoing transcatheter pulmonary valve implantation in the US Melody valve investigational trial

Comparison of right ventricular volume measurement between segmented k‐space gradient‐echo and steady‐state free precession magnetic resonance imaging

Preoperative Thresholds for Pulmonary Valve Replacement in Patients With Corrected Tetralogy of Fallot Using Cardiovascular Magnetic Resonance

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