Homologous chemiluminescence resonance energy transfer on the interface of WS2 quantum dots for monitoring photocatalytic H2O2 evaluation

Colloidal Quantum Dots as an Emerging Vast Platform and Versatile Sensitizer for Singlet Molecular Oxygen Generation

“…Similarly, Sun et al described the generation of 1 O 2 for WS 2 by the decomposition of H 2 O 2 in the presence of sodium hypochlorite. It was found that NaClO oxidized W­(IV) of WS 2 to W­(VI) which subsequently reacted with H 2 O 2 to generate 1 O 2 and peroxotungstate . TMD has been proposed to couple with other inorganic materials for enhanced 1 O 2 generation and photodynamic therapy purposes.…”

“…Excessive consumption of oxygen and vascular shutdown during PDT results in hypoxia, thus reducing the therapeutic efficacy and preventing the full therapeutic response. Moreover, solid tumors have regions of intrinsic hypoxia because of the compromised microcirculation and decreased perfusion. ,, Therefore, QDs can act as hydrogenase-type catalysts and convert hydrogen peroxide (H 2 O 2 ), which may be present in high concentration in tumors, into 3 O 2 . , QDs provide us the opportunity to use either as an individual sensitizer of 1 O 2 generation (via TET or charge transfer) ,,− or by linking to some other sensitizer acceptor molecules, ,,,, thus acting like versatile sensitizers for 1 O 2 generation (Table ). The size-dependent confinement of excitons ensures the photophysics of QDs to position them strategically and selectively precise to an absorption profile of a molecular acceptor for potential energy transfer via FRET or TTET processes. ,,,− , It is noteworthy that the QDs also present variable shape morphology such as spheres, wires, rods, and platelets coupled with modifiable surface chemistry by depositing different anionic- or cationic-rich inorganic materials or molecular surface ligands.…”

“… 8 , 13 , 53 Therefore, QDs can act as hydrogenase-type catalysts and convert hydrogen peroxide (H 2 O 2 ), which may be present in high concentration in tumors, into 3 O 2 . 106 , 115 QDs provide us the opportunity to use either as an individual sensitizer of 1 O 2 generation (via TET or charge transfer) 5 , 53 , 61 − 65 or by linking to some other sensitizer acceptor molecules, 21 , 53 , 63 , 66 , 67 thus acting like versatile sensitizers for 1 O 2 generation ( Table 1 ). The size-dependent confinement of excitons ensures the photophysics of QDs to position them strategically and selectively precise to an absorption profile of a molecular acceptor for potential energy transfer via FRET or TTET processes.…”

“…Summary of1 O 2 Generation by QDs and QD−PS Conjugates and Detection by Various Means (H 2 O 2 ), which may be present in high concentration in tumors, into3 O 2 106,115. QDs provide us the opportunity to use either as an individual sensitizer of 1 O 2 generation (via TET or charge transfer)5,53,61−65 or by linking to some other sensitizer acceptor molecules,21,53,63,66,67 thus acting like versatile sensitizers for 1 O 2 generation (Table…”

Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19

“…There are many kinds of LRET, mainly including fluorescence resonance energy transfer, bioluminescence resonance energy transfer, and chemiluminescence resonance energy transfer [ 208 ]. LRET has been applied widely for biomedical applications, such as clinical diagnosis, environmental monitoring, and food safety [ [210] , [211] , [212] ]. For bioassays, the donors and acceptors get close to each other by antibody-antigen interactions with LRET.…”