2023
DOI: 10.1002/jgm.3533
|View full text |Cite
|
Sign up to set email alerts
|

Homologous recombination repair gene‐based risk model predicts prognosis and immune microenvironment for primary lung cancer after previous malignancies

Abstract: BackgroundHomologous recombination repair (HRR) plays an important role in cancer development, drug resistance, and immune escape, but the role of HRR genes in primary lung cancer (PLC) after previous malignancies is unclear.MethodsWe used HRR‐related score constrcted by HRR genes to classify patients into two groups and compared clinical progression, differential genes, and their functions between them. Then, we constructed a prognostic risk model based on HRR‐related score and screened key differentially exp… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2023
2023
2023
2023

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
(1 citation statement)
references
References 70 publications
(92 reference statements)
0
1
0
Order By: Relevance
“…In addition, pesticide exposure seems to be related to a slight increase in DNA damage when compared with non-exposed people 13 . Thus, more DNA damage associated with intrinsic alterations in DNA repair pathways may be an important factor in cancer development [42][43][44] .…”
Section: Discussionmentioning
confidence: 99%
“…In addition, pesticide exposure seems to be related to a slight increase in DNA damage when compared with non-exposed people 13 . Thus, more DNA damage associated with intrinsic alterations in DNA repair pathways may be an important factor in cancer development [42][43][44] .…”
Section: Discussionmentioning
confidence: 99%