Homologous Resistant Groups (HRGs) in Multidrug Resistant Staphylococcus aureus Isolated from Retail Foods in Vadapalani, Chennai

Manoharan, Muthu Saravanan; Jayaraman, Sathishkumar; Illanchezian, Seethalakshmi; Jayasekar, Jasmine

doi:10.5580/103c

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“…The bacterium is known as one of the most frequent pathogens in both community and nosocomial infections, and it causes septicemia, endocarditis, osteomyelitis, abscesses, pneumonia, wound infections, impetigo, cutaneous rash, in addition to various toxin-mediated disease (1) . In addition the combinations of toxin-mediated virulence, invasiveness, and antibiotic resistance are also play a major role in these manifestations (2) . Blood stream infection is often associated with serious complications.…”

Section: Introducctionmentioning

confidence: 99%

Inhibition of Staphylococcus aureus enterotoxin genes by using plant extracts

Mohammed

Al-ani

Mohammed³

et al. 2018

Innovaciencia

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Introduction: Enterotoxigenic Staphylococcus aureus is an important pathogen that causes septicemia and bacteremia and is often associated with serious complications, such as endocarditis and osteomyelitis. Some Staphylococcus enterotoxins require only minute quantities to be toxic in humans. The present study focused on investigation how to remove this problematic issue. Objectives: This study was conducted to inhibit S. aureus enterotoxin genes that obtained from positive blood culture bottles of patients at the pediatric hospital in Sulaimania city. Methods: Twenty five isolates of S. aureus were isolated among 100 positive blood culture bottles and determined the strains that produce enterotoxins through culture method. Then, the enterotoxin genes that located on plasmids were cured by two medicinal plants (Eugenia caryophyllata and Cinnamomum zeylanicum). Results: The results showed that nine out of 25 isolates were released enterotoxins from which the plasmid encoding enterotoxin genes were confirmed in four of them. And, two of the isolates were transferred to recipient DH10B E. coli isolate successfully. Methanol extracts of (E. caryophyllata and C. zeylanicum) were used at sub minimum inhibition concentration as curing agents. Conclusion: Methanol extracts of (E. caryophyllata and C. zeylanicum) have grate effect on eliminating the plasmidsencoding enterotoxin gene of S. aureus.

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Section: Introducctionmentioning

confidence: 99%