We study the homotopy groups of open books in terms of those of their pages and bindings. Under homotopy theoretic conditions on the monodromy we prove an integral decomposition result for the based loop space on an open book, and under more relaxed conditions we prove a rational loop space decomposition. The latter case allows for a rational dichotomy theorem for open books, as an extension of the classical dichotomy in rational homotopy theory. As a direct application, we show that for Milnor’s open book decomposition of an odd sphere with monodromy of finite order the induced action of the monodromy on the homology groups of its page cannot be nilpotent.