THIS REPORT is concerned with a further evaluation of auxiliary canine homotransplantation of the liver and with the attempted application of such a procedure for the treatment of three patients.
MethodsThere were 33 mongrel dogs weighing 17.7 to 22.2 kg (average, 17.5 kg) (39 to 49 Ib [average, 38.5 lb]) used as recipients. The experiment was completed in 11 animals. The other 22 died early of anesthetic, technical, and septic complications and are excluded from further discussion. In the 11 test dogs the donors (weight 9.5 to 20 kg [21 to 44 lb])were smaller than their recipients, the average weight being 13.6 kg (30 lb). The general surgical techniques and the studies obtained postoperatively were similar to those described in previous publica-tion~.',~ The average ischemia time for the cooled TABLE 1.-Dogs With Patent Portal Venous and Hepatic Arterial Inflow to the Homograft Weight of Welght of Dog Survival, Transplant, Host Llver. No. Days Om Om