2013
DOI: 10.1055/s-0032-1328330
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Hop Extracts and Hop Substances in Treatment of Menopausal Complaints

Abstract: Hop extract is a long used medicinal product and, regarding hormonal activities, in 1999 a number of prenylflavanones have been identified as its major constituents with 8-prenylnaringenin (8-PN) being the main active estrogenic compound. There have been several in vivo studies performed that demonstrate the potential of hop extract and the single compound 8-PN to alleviate climacteric sympto… Show more

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Cited by 61 publications
(42 citation statements)
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“…257 Efforts have also been made to obtain isoxanthohumol cells during testosterone formation from pregnenolone [64].…”
mentioning
confidence: 99%
“…257 Efforts have also been made to obtain isoxanthohumol cells during testosterone formation from pregnenolone [64].…”
mentioning
confidence: 99%
“…Drugs that are synthesised from natural products have a key role in pharmaceutical care [36–38] and have proven to be critical sources of potential products for osteoporosis treatment [39, 40]. We have shown that KLEXJ boosts ALP activity and BMP-2 production in osteoblasts via the PI3K/Akt-NF-κB pathway and hence may be suitable in the treatment of osteoporosis.…”
Section: Discussionmentioning
confidence: 99%
“…More recently it was proposed to be used by women for the attenuation of menopausal symptoms [6,7]. Along these lines, we recently observed biological effects of the hops extract regarding ovariectomy-induced deterioration of the bone.…”
Section: Introductionmentioning
confidence: 93%