Hopelessness and Depression Predict Sarcopenia in Advanced CKD and Dialysis: A Multicenter Cohort Study

Kurita, Noriaki; Wakita, Takafumi; Fujimoto, Shino; Yanagi, Mai; Koitabashi, Kenichiro; Suzuki, Tomo; Yazawa, Masahiko; Kawarazaki, Hiroo; Shibagaki, Yugo; Ishibashi, Yoshitaka

doi:10.1007/s12603-020-1556-4

Cited by 32 publications

(25 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Depressed patients have more hopelessness and are at a higher likelihood of experiencing sarcopenia within one year of onset of depressive symptoms. Due to sarcopenia, these patients have severe loss of muscle mass leading to severe difficulties in performing tasks and impaired functioning [21].…”

Section: Discussionmentioning

confidence: 99%

Depression Impairs Level of Functioning in Chronic Kidney Disease Inpatients: A Case-Control Study

Virani¹,

Shah²,

Haneef³

et al. 2021

Cureus

View full text Add to dashboard Cite

To evaluate the difference in demographics and clinical correlates during hospitalization for chronic kidney disease (CKD) between patients with depression and those without depression, and its impact on the severity of illness and in-hospital mortality. MethodsWe conducted a case-control study and included 2,296 adult inpatients (age ≥18 years) with a primary discharge diagnosis of CKD using the nationwide inpatient sample (NIS). We used propensity score matching to extract the cases i.e., CKD inpatients with depression (N = 1,264) and the controls i.e. CKD inpatients without depression (N = 1,032). The matching was done based on demographic characteristics of age at admission, sex, race, and median household income. Our outcomes of interest are the severity of illness and all-cause in-hospital mortality. All patient refined drg (APR-DRG) are allocated using health information systems software by the NIS and the severity of illness within each base APR-DRG was classified into minor, moderate, or major loss of body functions. Binomial logistic regression analysis was conducted to find the odds ratio (OR) of association for major loss of function in CKD inpatients with depression, and this model was adjusted for potential confounders of congestive heart failure (CHF), coronary artery disease (CAD), diabetes, hypertension, obesity, and tobacco abuse, and utilization of hemodialysis. ResultsA higher proportion of CKD inpatients with depression had a statistically significant higher prevalence of major loss of function (49.8% vs. 40.3% in non-depressed). There was a statistically significant difference with higher utilization of hemodialysis in CKD inpatients with depression (76.2% vs. 70.7% in nondepressed). The all-cause in-hospital mortality rate was lower in CKD inpatients with depression (2.1% vs. 3.5% in non-depressed). After controlling the logistic regression model for potential comorbidities and utilization of hemodialysis, depression was associated with increased odds (OR 1.46; 95% CI 1.227 -1.734) for major loss of function versus in non-depressed CKD inpatients ConclusionComorbid depression increases the likelihood of major loss of functioning in CKD inpatients by 46%. Treating depression can allow patients to better cope emotionally and physically with CKD and other comorbidities and significantly improve the patient's quality of life (QoL) and health outcome.

show abstract

Section: Discussionmentioning

confidence: 99%

Depression Impairs Level of Functioning in Chronic Kidney Disease Inpatients: A Case-Control Study

Virani¹,

Shah²,

Haneef³

et al. 2021

Cureus

View full text Add to dashboard Cite

show abstract

“…Moreover, further research is needed to ascertain if SOC is conceptually different from self-efficacy, hope, and resilience. This is an important question to address specifically in this patient-population, especially that, for example, studies have shown that hope is associated with a decreased burden of fluid and dietary restriction in dialysis patients [ 75 ] and is associated with a decreased incidence of the decline in physical function [ 76 ].…”

Section: Discussionmentioning

confidence: 99%

The association between sense of coherence and quality of life: a cross-sectional study in a sample of patients on hemodialysis

Sawma

Sanjab

2022

BMC Psychol

View full text Add to dashboard Cite

Background Patients on hemodialysis universally experience detriments in their general quality of life (QOL). Sense of coherence (SOC) is a long-standing factor that affects QOL. Nevertheless, the association between SOC and QOL in patients on hemodialysis was seldom investigated. Our research aims to study this association in a sample of Lebanese adult patients on hemodialysis. Methods In this cross-sectional study, SOC was measured using the short version of the “Orientation of Life" scale (SOC-13). QOL was assessed using the Kidney Disease Quality of Life- Short Form (KDQOL-SF). The association between SOC and QOL and its submodalities was first explored using Pearson Correlation and multivariate linear regression analyses, controlling for sociodemographic variables and medical variables. Results 157 patients on hemodialysis (mean(SD) age: 62.1(13.81) years; 58.6% males) were included. Mean QOL score was 51.65 and that of SOC was 48.06. SOC was strongly corrected with the total QOL (r = 0.832; p value < 0.001), as well as its physical functioning (r = 0.767; p value < 0.001), emotional functioning (r = 0.757; p value < 0.001), cognitive functioning (r = 0.740; p value < 0.001), and social functioning (r = 0.773; p value < 0.001) submodailties. SOC was moderately correlated with professional functioning submodality of QOL (r = 0.618; p value < 0.001), but not correlated with the satisfaction with the quality of care (r = 0.052; p = 0.520). Within the regression models accounting for sociodemographic and medical variables, SOC was significantly associated with the total QOL (unstandardized B = 0.803; 95% CI 0.714, 0.893), physical functioning (unstandardized B = 0.761; standardized B = 0.763; 95% CI 0.661, 0.861), emotional functioning (unstandardized B = 1.205; standardized B = 0.757; 95% CI 1.037, 1.372), professional functioning (unstandardized B = 1.142; standardized B = 0.498; 95% CI 0.843, 1.442), cognitive functioning (unstandardized B = 1.239; standardized B = 0.739; 95% CI 1.058, 1.420), and social functioning (unstandardized B = 0.912; standardized B = 0.768; 95% CI 0.790, 1.034). Conclusions In a sample of adult patients on hemodialysis, SOC was positively significantly associated with QOL and its submodalities, expect the satisfaction with the quality of care. The confirmation of the general hypothesis that relates the SOC with the QOL encourages more salutogenic research among this patient population.

show abstract

“…This finding indicates that hopelessness is a distinct entity from depression and has distinct consequences compared with those from depression. [29, 30] Furthermore, this perspective may be clinically important since loss of hope can also be observed in the absence of depression. [31]…”

Section: Discussionmentioning

confidence: 99%

Trust in the attending rheumatologist, health-related hope, and medication adherence among Japanese patients with systemic lupus erythematosus: the TRUMP²-SLE project

Kurita

Oguro

Miyawaki

et al. 2022

Preprint

Self Cite

View full text Add to dashboard Cite

Objectives Poor medication adherence among patients with systemic lupus erythematosus (SLE) is a critical problem associated with adverse outcomes. This study examined the relationship between trust in one's physician and goal-oriented thinking, hope, and medication adherence among Japanese patients with SLE who were ethnically matched to their physicians. Methods This cross-sectional study was conducted in the rheumatology outpatient clinics at five academic centers. Patients with SLE who were prescribed oral medications were included. The main exposure was trust in one's physician measured via the 5-item Japanese version of the Wake Forest Physician Trust Scale and the 18-item Health-related Hope Scale, with each score ranging from 0 to 100 points. The outcome was medication adherence measured using the 12-item Medication Adherence Scale with scores ranging from 5 to 60 points. A general linear model was created after adjusting for demographics, socioeconomic status, disease activity, disease duration, basic health literacy, depression, medication variables, experiencing adverse effects, and concerns regarding lupus medications. Results Altogether, 373 patients with SLE were included. The mean age of the patients was 46.4 years, and among them, 329 (88.2%) were women. Both trust in one's physician (per 10-point increase: 0.88, 95% confidence interval [95%CI]: 0.53 to 1.24) and the Health-related Hope score (per 10-point increase: 0.64, 95%CI: 0.33 to 0.95) were associated with better medication adherence. Conclusions Physician communication to build trust and coaching on self-management to maintain or achieve what is important in the patient's life and to enhance hope may lead to better medication adherence.

show abstract

Hopelessness and Depression Predict Sarcopenia in Advanced CKD and Dialysis: A Multicenter Cohort Study

Cited by 32 publications

References 32 publications

Depression Impairs Level of Functioning in Chronic Kidney Disease Inpatients: A Case-Control Study

Depression Impairs Level of Functioning in Chronic Kidney Disease Inpatients: A Case-Control Study

The association between sense of coherence and quality of life: a cross-sectional study in a sample of patients on hemodialysis

Trust in the attending rheumatologist, health-related hope, and medication adherence among Japanese patients with systemic lupus erythematosus: the TRUMP²-SLE project

Contact Info

Product

Resources

About

Hopelessness and Depression Predict Sarcopenia in Advanced CKD and Dialysis: A Multicenter Cohort Study

Cited by 32 publications

References 32 publications

Depression Impairs Level of Functioning in Chronic Kidney Disease Inpatients: A Case-Control Study

Depression Impairs Level of Functioning in Chronic Kidney Disease Inpatients: A Case-Control Study

The association between sense of coherence and quality of life: a cross-sectional study in a sample of patients on hemodialysis

Trust in the attending rheumatologist, health-related hope, and medication adherence among Japanese patients with systemic lupus erythematosus: the TRUMP2-SLE project

Contact Info

Product

Resources

About

Trust in the attending rheumatologist, health-related hope, and medication adherence among Japanese patients with systemic lupus erythematosus: the TRUMP²-SLE project