Horizon Scanning in Cancer Genomics: How Advances in Genomic Medicine Will Change Cancer Care Over the Next Decade

Seed, Lydia

doi:10.1007/s40142-021-00200-7

Cited by 4 publications

(2 citation statements)

References 42 publications

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“…Genomics has improved the diagnosis and treatment of diseases such as cancer (Brittain et al 2017;Peterson et al 2019;Seed 2021) and cardiac disease (Khera et al 2016;Pasipoularides 2018), and reduced healthcare costs and treatment burden for individuals (Bilkey et al 2019;Stark et al 2019). For example, the identification of BRCA gene variants for breast cancer or MSH2, MSH6 and MLH1 for colon and extracolonic cancers have resulted in screening programs and therapies that have changed the trajectory and outcomes of these diseases.…”

Section: Introductionmentioning

confidence: 99%

Leading Canadian Nurses into the Genomic Era of Healthcare

Limoges¹,

Pike²,

Dewell³

et al. 2022

cjnl

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Genomics is having a profound impact on every aspect of healthcare. To support nurses to develop genomic literacy and integrate genomics into care, an engagement framework was created. The framework uses principles of nursing intraprofessional collaboration, the knowledge-to-action cycle and the diffusion of innovations theory. This framework was used to identify six key priorities for action and leadership strategies to accelerate and sustain the nurses' engagement with genomics. With leadership and genomic literacy, nurses can fully participate in the creation and implementation of new care pathways, deliver education, advance research linked to genomics and improve patient experience and health outcomes.

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Section: Introductionmentioning

confidence: 99%

Leading Canadian Nurses into the Genomic Era of Healthcare

Limoges¹,

Pike²,

Dewell³

et al. 2022

cjnl

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“…Targeting identifiable, relevant gene pathways and networks specific to an individuals' genomic and molecular profile is a strategy that has been shown to improve treatment responses [2]. This genomically targeted personalized medicine strategy is effective across many medical disciplines, including oncology and neurology [2][3][4]. Components that convey individuality are of paramount importance for the successful treatment of ASD.…”

mentioning

confidence: 99%

Utilizing Genomically Targeted Molecular Data to Improve Patient-Specific Outcomes in Autism Spectrum Disorder

Hausman-Cohen

LaValley²,

Way

et al. 2022

IJMS

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Molecular biology combined with genomics can be a powerful tool for developing potential intervention strategies for improving outcomes in children with autism spectrum disorders (ASD). Monogenic etiologies rarely cause autism. Instead, ASD is more frequently due to many polygenic contributing factors interacting with each other, combined with the epigenetic effects of diet, lifestyle, and environment. One limitation of genomics has been identifying ways of responding to each identified gene variant to translate the information to something clinically useful. This paper will illustrate how understanding the function of a gene and the effects of a reported variant on a molecular level can be used to develop actionable and targeted potential interventions for a gene variant or combinations of variants. For illustrative purposes, this communication highlights a specific genomic variant, SHANK3. The steps involved in developing molecularly genomically targeted actionable interventions will be demonstrated. Cases will be shared to support the efficacy of this strategy and to show how clinicians utilized these targeted interventions to improve ASD-related symptoms significantly. The presented approach demonstrates the utility of genomics as a part of clinical decision-making.

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Revolutionizing healthcare and medicine: The impact of modern technologies for a healthier future—A comprehensive review

Thacharodi,

Singh,

Meenatchi

et al. 2024

Health Care Science

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The increasing integration of new technologies is driving a fundamental revolution in the healthcare sector. Developments in artificial intelligence (AI), machine learning, and big data analytics have completely transformed the diagnosis, treatment, and care of patients. AI‐powered solutions are enhancing the efficiency and accuracy of healthcare delivery by demonstrating exceptional skills in personalized medicine, early disease detection, and predictive analytics. Furthermore, telemedicine and remote patient monitoring systems have overcome geographical constraints, offering easy and accessible healthcare services, particularly in underserved areas. Wearable technology, the Internet of Medical Things, and sensor technologies have empowered individuals to take an active role in tracking and managing their health. These devices facilitate real‐time data collection, enabling preventive and personalized care. Additionally, the development of 3D printing technology has revolutionized the medical field by enabling the production of customized prosthetics, implants, and anatomical models, significantly impacting surgical planning and treatment strategies. Accepting these advancements holds the potential to create a more patient‐centered, efficient healthcare system that emphasizes individualized care, preventive care, and better overall health outcomes. This review's novelty lies in exploring how these technologies are radically transforming the healthcare industry, paving the way for a more personalized and effective healthcare for all. It highlights the capacity of modern technology to revolutionize healthcare delivery by addressing long‐standing challenges and improving health outcomes. Although the approval and use of digital technology and advanced data analysis face scientific and regulatory obstacles, they have the potential for transforming translational research. as these technologies continue to evolve, they are poised to significantly alter the healthcare environment, offering a more sustainable, efficient, and accessible healthcare ecosystem for future generations. Innovation across multiple fronts will shape the future of advanced healthcare technology, revolutionizing the provision of healthcare, enhancing patient outcomes, and equipping both patients and healthcare professionals with the tools to make better decisions and receive personalized treatment. As these technologies continue to develop and become integrated into standard healthcare practices, the future of healthcare will probably be more accessible, effective, and efficient than ever before.

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Horizon Scanning in Cancer Genomics: How Advances in Genomic Medicine Will Change Cancer Care Over the Next Decade

Cited by 4 publications

References 42 publications

Leading Canadian Nurses into the Genomic Era of Healthcare

Leading Canadian Nurses into the Genomic Era of Healthcare

Utilizing Genomically Targeted Molecular Data to Improve Patient-Specific Outcomes in Autism Spectrum Disorder

Revolutionizing healthcare and medicine: The impact of modern technologies for a healthier future—A comprehensive review

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