Hormonal contraceptives as a risk factor for cerebral venous and sinus thrombosis

Saadatnia, Mohammad; Tajmirriahi, Marzieh

doi:10.1111/j.1600-0404.2007.00824.x

Cited by 32 publications

(35 citation statements)

References 49 publications

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“…20,22,36,41,50,58 It is well known that thirdgeneration contraceptives substantially increase the risk of CVST. 20 Likewise, the risk of CVST is increased during the last trimester of pregnancy and during the postdelivery period.…”

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confidence: 99%

Cerebral venous sinus thrombosis: review of the demographics, pathophysiology, current diagnosis, and treatment

Filippidis¹,

Kapsalaki

Patramani

et al. 2009

FOC

121

160

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Cerebral venous sinus thrombosis (CVST) is a rare clinicopathological entity. The incidence of CVST in children and neonates has been reported to be as high as 7 cases per million people, whereas in adults the incidence is 3–4 cases per million. The predisposing factors to this condition are mainly genetic and acquired prothrombotic states and infection. The clinical picture of CVST is nonspecific, highly variable, and can mimic several other clinical conditions. Diagnosis of CVST is established with the implementation of neuroimaging studies, especially MR imaging and venography. Identification and elimination of the underlying cause, anticoagulation, proper management of intracranial hypertension, and anticonvulsant prophylaxis constitute cornerstones of CVST treatment. Newer treatment strategies such as endovascular thrombolysis and decompressive craniectomy have been recently used in the treatment of patients with CVST with variable success rates. Further clinical research must be performed to delineate the exact role of these newer treatments in the management of severe cases of CVST. The recent advances in the diagnosis and treatment of patients with CVST have significantly lowered the associated mortality and morbidity and have improved the outcome of these patients.

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mentioning

confidence: 99%

Cerebral venous sinus thrombosis: review of the demographics, pathophysiology, current diagnosis, and treatment

Filippidis¹,

Kapsalaki

Patramani

et al. 2009

FOC

121

160

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“…Its epidemiology has changed over past few decades. [11] Its increasing prevalence may be attributed to not only increased ease of diagnosis by modern imaging tools such as magnetic resonance imaging (MRI), but also to the increment of underlying causes including use of oral contraceptive pills (OCPs). [11,12] Cerebral venoussinus thrombosis seems relatively more frequent in South Asia and Middle East.…”

Section: Discussionmentioning

confidence: 99%

“…[11] Its increasing prevalence may be attributed to not only increased ease of diagnosis by modern imaging tools such as magnetic resonance imaging (MRI), but also to the increment of underlying causes including use of oral contraceptive pills (OCPs). [11,12] Cerebral venoussinus thrombosis seems relatively more frequent in South Asia and Middle East. [11] In this present study, we were included a total of 40 cases of cortical venous thrombosis with age group of 15 to > 60 years.…”

Section: Discussionmentioning

confidence: 99%

“…[11,12] Cerebral venoussinus thrombosis seems relatively more frequent in South Asia and Middle East. [11] In this present study, we were included a total of 40 cases of cortical venous thrombosis with age group of 15 to > 60 years. Higher incidence 15 (37.5%) of cortical venous thrombosis was seen in young age group patients (15-30 years) patients.…”

Section: Discussionmentioning

confidence: 99%

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Clinical Profile of Patients with Cortical venous Thrombosis: A Hospital Based Study

Nandani¹

2018

jmscr

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“…The mean age is 37-38 years, but it can be seen in all ages (1,2). It is associated with infections, neoplasm, pregnancy, puerperium, systemic diseases, dehydration, oral contraceptives (OCPs), and coagulopathies (3,4). In 30% of the patients, underlying pathology could not be identified (2).…”

Section: Introductionmentioning

confidence: 99%

Cerebral venous sinus thrombosis: gender differences in ten years experience

Özcan¹,

Meral²,

Özben³

et al. 2013

Dusunen Adam

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Cerebral venous sinus thrombosis: gender differences in ten years experienceObjective: Cerebral venous sinus thrombosis (CVST) is an uncommon subtype of stroke. CVST is much more common in women than men with a ratio of three to one. This women preponderance is attributed to gender-specific risk factors (GSRF). In many patients, symptoms develop over days or weeks. In some patients, clinical presentations are nonspesific. Patients and Methods: We reviewed the records of patients with CVST treated at Neurology department of Haseki Training and Research Hospital between 2001-2011, which diagnoses were confirmed with cranial magnetic resonance imaging (MRI) and magnetic resonance venography (MRV). Thirty-four patients were included the study. Women/men ratio was 3.25/1. We analyzed the demographic features, comorbid conditions, clinical presentation, neuroradiological findings. Results: Thirty-four patients were included the study. Headache was present in all patients and it was present as isolated in 47.1% (n=16) of the patients. In 52.9% (n=18) of the patients onset of the symptoms were subacute, 29.4% (n=10) chronic, 17.6 (n=6) acute. Of all patients, 76.5% (n=26) were women. Transverse sinus was the mostly affected sinus as either isolated or with the other CSVT in both groups (in 20 women and 8 men). The most common presentation symptom (43.78%) in women was headache whereas; it was intracranial hypertension (34.78%) in men. Half of our women patients with GRSF; 7 (26.92%) women were oral contraceptives user and 5 (15.38%) women were in pregnancy or puerperium period. Conclusion: We have found differences between women and men in the presentation and risk factors. Key words: Gender, risk factors, sinus thrombosis ÖZET Serebral sinus ven trombozu: On yıllık tecrübede cinsiyet farklılıklarıAmaç: Serebral sinus ven trombozu (SSVT) inmenin nadir nedenlerindendir. SSVT kadınlarda erkekleklere göre üçe bir oranında daha sık görülür. Bu kadın baskınlığı cinsiyete özgü rik faktörlerine bağlanmaktadır. Hastaların çoğunda semptomlar günler veya haftalar içinde yerleşmektedir. Bazı hastalarda klinik görünüm nonspesifik olmaktadır. Yöntem: Haseki Eğitim ve Araştırma Hastanesinde 2001-2011 yılları arasında cranial MR ve MR venografi ile tanısı doğrulanarak SSVT tedavisi almış hasta kayıtlarını inceledik. Çalışmaya otuz dört hasta dahil edildi. Kadın/ erkek oranı 3.25/1 idi. Hastaların demografik özelliklerini, komorbid durumlarını, klinik görünümlerini, nöroradyolajik bulgularını inceledik. Bulgular: Çalışmaya otuz dört hasta dahil edildi. Başağrısı hastaların %47.1'inde (n=16) izole olmak üzere tüm hastalarda mevcuttu. Semptomların başlangıcı hastaların %52.9'unda (n=18) subakut, %29.4'ünde (n=10) kronik, %17.6'sında (n=6) akut idi. Tüm hastaların %76.5'i (n=26) kadındı. Her iki cinsiyette de en sık etkilenen sinus transvers sinus olarak saptandı (20 kadın ve 8 erkek). Başvurudaki en sık semptom kadınlarda başağrısı (%43.78) iken, erkeklerde intracranial hipertansiyon (%34.78) idi. Cinsiyete özgü risk faktörü sap...

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Hormonal contraceptives as a risk factor for cerebral venous and sinus thrombosis

Cited by 32 publications

References 49 publications

Cerebral venous sinus thrombosis: review of the demographics, pathophysiology, current diagnosis, and treatment

Cerebral venous sinus thrombosis: review of the demographics, pathophysiology, current diagnosis, and treatment

Clinical Profile of Patients with Cortical venous Thrombosis: A Hospital Based Study

Cerebral venous sinus thrombosis: gender differences in ten years experience

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