Hormonal Control of Tumor Formation in Radish

Matveeva, T. V.; Frolova, Nadezhda; Smets, RafaÃ«l; Додуева, И. Е.; Buzovkina, I. S.; Onckelen, Harry Van; Лутова, Л. А.

doi:10.1007/s00344-004-0004-8

Cited by 29 publications

(27 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Previous studies have shown that initiation of many types of tumors (genetic tumors in tumor radish lines and tobacco lines, and nodules on legume roots) in plants involves a local increase in the endogenous hormone CTK (Ichikawa and Syono, ; Lohar et al ., ; Matveeva et al ., ; Il'ina et al ., ; Oldroyd, ). Our results suggested the formation of fruit warts was also correlated with high CTK content (Figures a).…”

Section: Discussionmentioning

confidence: 99%

“…Warty fruit phenotype is correlated with high cytokinin (CTK) content Matveeva et al (2004) studied the genetic tumors of the crop-root in tumor radish lines and showed that changes in the concentration of endogenous CTK induced tumor initiation. Oldroyd (2007) found that formation of the root nodule was also correlated with high CTK content.…”

Section: Subcellular Localization and Expression Pattern Of Tumentioning

confidence: 99%

See 1 more Smart Citation

Tuberculate fruit gene Tu encodes a C₂H₂ zinc finger protein that is required for the warty fruit phenotype in cucumber (Cucumis sativus L.)

Yang

Zhang

et al. 2014

The Plant Journal

View full text Add to dashboard Cite

SUMMARYCucumber fruits that have tubercules and spines (trichomes) are known to possess a warty (Wty) phenotype. In this study, the tuberculate fruit gene Tu was identified by map-based cloning, and was found to encode a transcription factor (TF) with a single C 2 H 2 zinc finger domain. Tu was identified in all 38 Wty lines examined, and was completely absent from all 56 non-warty (nWty) lines. Cucumber plants transgenic for Tu (TCP) revealed that Tu was required for the Wty fruit phenotype. Subcellular localization showed that the fusion protein GFP-Tu was localized mainly to the nucleus. Based on analyses of semi-quantitative and quantitative reverse transcription polymerase chain reaction (RT-PCR), and mRNA in situ hybridization, we found that Tu was expressed specifically in fruit spine cells during development of fruit tubercules. Moreover, cytokinin (CTK) content measurements and cytological observations in Wty and nWty fruits revealed that the Wty fruit phenotype correlated with high endogenous CTK concentrations. As a result of further analyses on the transcriptomic profile of the nWty fruit epidermis and TCP fruit warts, expression of CTKassociated genes, and hormone content in nWty fruit epidermis, Wty fruit warts and epidermis, and TCP fruit warts and epidermis, we found that Tu probably promoted CTK biosynthesis in fruit warts. Here we show that Tu could not be expressed in the glabrous and tubercule-free mutant line gl that contained Tu, this result that futher confirmed the epistatic effect of the trichome (spine) gene Gl over Tu. Taken together, these data led us to propose a genetic pathway for the Wty fruit trait that could guide future mechanistic studies.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Subcellular Localization and Expression Pattern Of Tumentioning

confidence: 99%

Tuberculate fruit gene Tu encodes a C₂H₂ zinc finger protein that is required for the warty fruit phenotype in cucumber (Cucumis sativus L.)

Yang

Zhang

et al. 2014

The Plant Journal

View full text Add to dashboard Cite

show abstract

“…Некоторые исследователи считают, что синтез фитогормонов у этих организмов осуществляется симбиотическими бакте-риями (Giron, Glevarec, 2014). Повышение содержания эндогенных фитогормонов, в особенности ИУК и ЦК, было показано также для спонтанных опухолей разных типов (Ahuja, 1998;Matveeva et al, 2004;Lee et al, 2004).…”

Section: галлы и опухоли: меристемы под ключ -заселение сегодняunclassified

Plant stem cells: unity and diversity

Додуева¹,

Tvorogova²,

Azarakhsh³

et al. 2016

Vestn. VOGiS

Self Cite

View full text Add to dashboard Cite

Stem cells are undifferentiated cells of multicellular organisms that can divide, self-renew and differentiate. Despite the differences of properties, general principles of the existence of stem cells can be distinguished in all multicellular organisms. In plants, stem cells are found in meristems -the structures that ensure the continuous growth of plant and provide material for the formation of various specialized tissues. There are numerous types of meristems: shoot and root apical meristems, lateral meristems (procambium, cambium, pericycle), as well as the so-called irregular meristems, developing under certain conditions (callus, meristems of symbiotic nodules, spontaneous and pathogen-induced tumors, etc.). For each of meristems, specific mechanisms of regulation, which are based on the interaction of plant hormones and the major groups of transcription factors, were identified. The activity of meristems is based on two opposite processes: proliferation and self-renewal of stem cells in the central part of the meristem and differentiation of specialized cells in the periphery. WOX-CLAVATA systems are a regulatory component conservative for different meristems and providing consistency of the composition of the meristem, as well as the balance of stem cell proliferation and differentiation. In this review, we will consider the similarities and differences between the principles of organization of stem cell niches in plants and animals, as well as in a variety of meristems of higher plants; special attention will be paid to the role of WOX-CLAVATA systems in maintaining meristems and their interaction with other meristem regulators.Keywords: stem cells; meristems; WOX; CLE-peptides; LRR-kinases; apical meristems; cambium; pericycle; callus; tumors; nodules.Стволовые клетки -недифференцированные клетки многоклеточ-ных организмов, способные делиться, самообновляться и диф-фе ренцироваться. Несмотря на существующие различия свойств, у всех многоклеточных организмов можно выделить общие прин-ципы существования стволовых клеток. У растений стволовые клетки находятся в меристемах -структурах, обеспечивающих непрерывный рост растения и предоставляющих материал для образования различных специализированных тканей. Выделяют разнообразные типы меристем: апикальные -побега и кор ня, латеральные (прокамбий, камбий, перицикл), а также так называемые нерегулярные, развивающиеся при определен-ных усло виях (каллус, меристемы симбиотических клубеньков, спонтан ные и патоген-индуцированные опухоли и т. д.). Для каж-дой из меристем выявлены специфические механизмы регуля-ции, для которых характерно взаимодействие фитогормонов и основных групп транскрипционных факторов. Активность меристем обусловлена двумя противоположных процессами: пролиферацией и самообновлением стволовых клеток в цен-тральной части меристемы и дифференцировкой специализиро-ванных клеток на периферии. Системы WOX-CLAVATA -консерва-тивный для разных меристем регуляторный компонент, который обеспечивает размер и постоянство состава меристемы, а также баланс ...

show abstract

“…Data on CLE gene expression in plant tumors were obtained on sponta neous tumors in inbred radish (Raphanus sativus var. radicula) lines [69], which arise as a result of pericycle cell proliferation in response to the elevated concen tration of endogenous cytokinins [70,71]. It was shown that even short treatment with cytokinins sup pressed expression of some CLE genes of group A (RsCLE19, RsCLE2, RsCLE5) in radish and enhanced expression of CLE genes of group B (RsCLE41).…”

Section: Cle Peptides Of Parasitic Nematodesmentioning

confidence: 99%

CLE peptides are universal regulators of meristem development

Додуева

Yurlova

Osipova

et al. 2011

Russ J Plant Physiol

Self Cite

View full text Add to dashboard Cite

Meristems are morphogenic plant tissues comprising the pool of stem cells initiating specialized tissues. The balance of stem cell proliferation and differentiation depends on antagonistic action of genes WOX encoding homeodomain containing transcription factors and CLAVATA like systems controlling their expression. The CLE (CLAVATA3/ENDOSPERM SURROUNDING REGION) peptides and their recep tor protein kinases comprise the basis of the CLAVATA like systems. Definite member of the family of CLE peptides (CLV3 in the shoot, CLE40 in the root, and CLE41/CLE44 in the procambium) are central regula tors of primary meristem development. The role of CLE peptides in the development of secondary meristems, such as nodule meristems of legumes, is studied. CLE peptides are found also outside the plant kingdom, e.g., parasitic nematodes. The review considers CLE peptides as universal regulators of meristem development.

show abstract

Hormonal Control of Tumor Formation in Radish

Cited by 29 publications

References 25 publications

Tuberculate fruit gene Tu encodes a C₂H₂ zinc finger protein that is required for the warty fruit phenotype in cucumber (Cucumis sativus L.)

Tuberculate fruit gene Tu encodes a C₂H₂ zinc finger protein that is required for the warty fruit phenotype in cucumber (Cucumis sativus L.)

Plant stem cells: unity and diversity

CLE peptides are universal regulators of meristem development

Contact Info

Product

Resources

About

Hormonal Control of Tumor Formation in Radish

Cited by 29 publications

References 25 publications

Tuberculate fruit gene Tu encodes a C2H2 zinc finger protein that is required for the warty fruit phenotype in cucumber (Cucumis sativus L.)

Tuberculate fruit gene Tu encodes a C2H2 zinc finger protein that is required for the warty fruit phenotype in cucumber (Cucumis sativus L.)

Plant stem cells: unity and diversity

CLE peptides are universal regulators of meristem development

Contact Info

Product

Resources

About

Tuberculate fruit gene Tu encodes a C₂H₂ zinc finger protein that is required for the warty fruit phenotype in cucumber (Cucumis sativus L.)

Tuberculate fruit gene Tu encodes a C₂H₂ zinc finger protein that is required for the warty fruit phenotype in cucumber (Cucumis sativus L.)